Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Functionalizing nanoparticles with biological molecules: develo** chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …

Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

EM Sletten, CR Bertozzi - Angewandte Chemie International …, 2009 - Wiley Online Library
The study of biomolecules in their native environments is a challenging task because of the
vast complexity of cellular systems. Technologies developed in the last few years for the …

Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

Choosing an effective protein bioconjugation strategy

N Stephanopoulos, MB Francis - Nature chemical biology, 2011 - nature.com
The collection of chemical techniques that can be used to attach synthetic groups to proteins
has expanded substantially in recent years. Each of these approaches allows new protein …

[HTML][HTML] Analysis and optimization of copper-catalyzed azide–alkyne cycloaddition for bioconjugation

V Hong, SI Presolski, C Ma, MG Finn - … Chemie (International ed. in …, 2009 - ncbi.nlm.nih.gov
Since its discovery in 2002, the copper-catalyzed azide-alkyne cycloaddition (CuAAC)[1]
reaction—the most widely recognized example of click chemistry [2]—has been rapidly …

The controlled display of biomolecules on nanoparticles: a challenge suited to bioorthogonal chemistry

WR Algar, DE Prasuhn, MH Stewart… - Bioconjugate …, 2011 - ACS Publications
Interest in develo** diverse nanoparticle (NP)-biological composite materials continues to
grow almost unabated. This is motivated primarily by the desire to simultaneously exploit the …

Bioengineered protein-based nanocage for drug delivery

EJ Lee, NK Lee, IS Kim - Advanced drug delivery reviews, 2016 - Elsevier
Nature, in its wonders, presents and assembles the most intricate and delicate protein
structures and this remarkable phenomenon occurs in all kingdom and phyla of life. Of these …

Protein cage assembly across multiple length scales

WM Aumiller, M Uchida, T Douglas - Chemical Society Reviews, 2018 - pubs.rsc.org
Within the materials science community, proteins with cage-like architectures are being
developed as versatile nanoscale platforms for use in protein nanotechnology. Much effort …

Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications

JA Johnson, YY Lu, JA Van Deventer… - Current opinion in chemical …, 2010 - Elsevier
Residue-specific incorporation of non-canonical amino acids into proteins allows facile
alteration and enhancement of protein properties. In this review, we describe recent …