Recent advances in triterpenoid pathway elucidation and engineering

S Dinday, S Ghosh - Biotechnology Advances, 2023 - Elsevier
Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …

Advances in biosynthesis, regulation, and metabolic engineering of plant specialized terpenoids

DA Nagegowda, P Gupta - Plant Science, 2020 - Elsevier
Plant specialized terpenoids are natural products that have no obvious role in growth and
development, but play many important functional roles to improve the plant's overall fitness …

Biosynthesis and the roles of plant sterols in development and stress responses

Y Du, X Fu, Y Chu, P Wu, Y Liu, L Ma, H Tian… - International Journal of …, 2022 - mdpi.com
Plant sterols are important components of the cell membrane and lipid rafts, which play a
crucial role in various physiological and biochemical processes during development and …

Withania somnifera (L.) Dunal: Phytochemistry, structure-activity relationship, and anticancer potential

D Tewari, V Chander, A Dhyani, S Sahu, P Gupta… - Phytomedicine, 2022 - Elsevier
Background Ayurveda is a highly recognized, well-documented, and well-accepted
traditional medicine system. This system utilizes many natural products in various forms for …

Natural withanolides, an update

G **a, S Cao, L Chen, F Qiu - Natural Product Reports, 2022 - pubs.rsc.org
Covering: March 2010 to December 2020. Previous review: Nat. Prod. Rep., 2011, 28, 705
This review summarizes the latest progress and perspectives on the structural classification …

Leveraging synthetic biology and metabolic engineering to overcome obstacles in plant pathway elucidation

BD Kwan, B Seligmann, TD Nguyen, J Franke… - Current opinion in plant …, 2023 - Elsevier
Major hurdles in plant biosynthetic pathway elucidation and engineering include the need
for rapid testing of enzyme candidates and the lack of complex substrates that are often not …

Agroinfiltration mediated scalable transient gene expression in genome edited crop plants

M Kaur, P Manchanda, A Kalia, FK Ahmed… - International Journal of …, 2021 - mdpi.com
Agrobacterium-mediated transformation is one of the most commonly used genetic
transformation method that involves transfer of foreign genes into target plants …

Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation

X Zhang, K Lin, Y Li - Plant Physiology and Biochemistry, 2020 - Elsevier
Phytosterols are a group of sterols exclusive to plants and fungi, but are indispensable to
humans because of their medicinal and nutritional values. However, current raw materials …

Enhanced production of withaferin A from the hairy root culture of Withania somnifera via synergistic effect of Methyl jasmonate and β-cyclodextrin

M Karami, MR Naghavi, J Nasiri, N Farzin… - Plant Physiology and …, 2024 - Elsevier
Due to low amounts of withanolides produced in some plants and high demand for various
applications, their biotechnological production is widely researched. The effects of two …

Yeast as a promising heterologous host for steroid bioproduction

S Xu, Y Li - Journal of Industrial Microbiology & Biotechnology …, 2020 - academic.oup.com
With the rapid development of synthetic biology and metabolic engineering technologies,
yeast has been generally considered as promising hosts for the bioproduction of secondary …