Direct methane oxidation by copper-and iron-dependent methane monooxygenases

FJ Tucci, AC Rosenzweig - Chemical reviews, 2024 - ACS Publications
Methane is a potent greenhouse gas that contributes significantly to climate change and is
primarily regulated in Nature by methanotrophic bacteria, which consume methane gas as …

Mechanism of action of ribosomally synthesized and post-translationally modified peptides

C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Alkane oxidation: methane monooxygenases, related enzymes, and their biomimetics

VCC Wang, S Maji, PPY Chen, HK Lee, SSF Yu… - Chemical …, 2017 - ACS Publications
Methane monooxygenases (MMOs) mediate the facile conversion of methane into methanol
in methanotrophic bacteria with high efficiency under ambient conditions. Because the …

Copper active sites in biology

EI Solomon, DE Heppner, EM Johnston… - Chemical …, 2014 - ACS Publications
On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

Particulate methane monooxygenase contains only mononuclear copper centers

MO Ross, F MacMillan, J Wang, A Nisthal, TJ Lawton… - Science, 2019 - science.org
Bacteria that oxidize methane to methanol are central to mitigating emissions of methane, a
potent greenhouse gas. The nature of the copper active site in the primary metabolic …

Reversing nitrogen fixation

N Lehnert, HT Dong, JB Harland, AP Hunt… - Nature Reviews …, 2018 - nature.com
The nitrogen cycle is one of the most important biogeochemical cycles on Earth because
nitrogen is an essential nutrient for all life forms. To supplement natural nitrogen fixation …

A tale of two methane monooxygenases

MO Ross, AC Rosenzweig - JBIC Journal of Biological Inorganic …, 2017 - Springer
Methane monooxygenase (MMO) enzymes activate O 2 for oxidation of methane. Two
distinct MMOs exist in nature, a soluble form that uses a diiron active site (sMMO) and a …

Enzymatic oxidation of methane

S Sirajuddin, AC Rosenzweig - Biochemistry, 2015 - ACS Publications
Methane monooxygenases (MMOs) are enzymes that catalyze the oxidation of methane to
methanol in methanotrophic bacteria. As potential targets for new gas-to-liquid methane …

Multicopper oxidases and oxygenases

EI Solomon, UM Sundaram, TE Machonkin - Chemical reviews, 1996 - ACS Publications
Copper is an essential trace element in living systems, present in the parts per million
concentration range. It is a key cofactor in a diverse array of biological oxidation-reduction …

Methanotrophs and copper

JD Semrau, AA DiSpirito, S Yoon - FEMS microbiology reviews, 2010 - academic.oup.com
Methanotrophs, cells that consume methane (CH4) as their sole source of carbon and
energy, play key roles in the global carbon cycle, including controlling anthropogenic and …