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African genetic diversity: implications for human demographic history, modern human origins, and complex disease map**
MC Campbell, SA Tishkoff - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …
important for reconstructing human evolutionary history and for understanding the genetic …
The evolution of human genetic and phenotypic variation in Africa
MC Campbell, SA Tishkoff - Current biology, 2010 - cell.com
Africa is the birthplace of modern humans, and is the source of the geographic expansion of
ancestral populations into other regions of the world. Indigenous Africans are characterized …
ancestral populations into other regions of the world. Indigenous Africans are characterized …
Inferring human population size and separation history from multiple genome sequences
S Schiffels, R Durbin - Nature genetics, 2014 - nature.com
The availability of complete human genome sequences from populations across the world
has given rise to new population genetic inference methods that explicitly model ancestral …
has given rise to new population genetic inference methods that explicitly model ancestral …
Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data
RN Gutenkunst, RD Hernandez, SH Williamson… - PLoS …, 2009 - journals.plos.org
Demographic models built from genetic data play important roles in illuminating prehistorical
events and serving as null models in genome scans for selection. We introduce an inference …
events and serving as null models in genome scans for selection. We introduce an inference …
Bayesian inference of ancient human demography from individual genome sequences
Whole-genome sequences provide a rich source of information about human evolution.
Here we describe an effort to estimate key evolutionary parameters based on the whole …
Here we describe an effort to estimate key evolutionary parameters based on the whole …
Demographic history and rare allele sharing among human populations
High-throughput sequencing technology enables population-level surveys of human
genomic variation. Here, we examine the joint allele frequency distributions across …
genomic variation. Here, we examine the joint allele frequency distributions across …
Species delimitation with gene flow
Species are commonly thought to be evolutionarily independent in a way that populations
within a species are not. In recent years, studies that seek to identify evolutionarily …
within a species are not. In recent years, studies that seek to identify evolutionarily …
Genome-wide patterns of population structure and admixture in West Africans and African Americans
Quantifying patterns of population structure in Africans and African Americans illuminates
the history of human populations and is critical for undertaking medical genomic studies on …
the history of human populations and is critical for undertaking medical genomic studies on …
Length distributions of identity by descent reveal fine-scale demographic history
Data-driven studies of identity by descent (IBD) were recently enabled by high-resolution
genomic data from large cohorts and scalable algorithms for IBD detection. Yet, haplotype …
genomic data from large cohorts and scalable algorithms for IBD detection. Yet, haplotype …
The environmental context for the origins of modern human diversity: a synthesis of regional variability in African climate 150,000–30,000 years ago
We synthesize African paleoclimate from 150 to 30 ka (thousand years ago) using 85
diverse datasets at a regional scale, testing for coherence with North Atlantic …
diverse datasets at a regional scale, testing for coherence with North Atlantic …