Molecular biology of aquaporins

C Li, W Wang - Aquaporins, 2017 - Springer
Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …

Aquaporin-3 in cancer

S Marlar, HH Jensen, FH Login, LN Nejsum - International journal of …, 2017 - mdpi.com
Increasing evidence suggests that the water/glycerol channel aquaporin-3 (AQP3) plays a
pivotal role in cancer metastasis. AQP3 knockout mice were resistant to skin tumor formation …

Aquaporins differentially regulate cell‐cell adhesion in MDCK cells

FH Login, HH Jensen, GA Pedersen… - The FASEB …, 2019 - Wiley Online Library
Plasticity of epithelial cell‐cell adhesion is vital in epithelial homeostasis and is regulated in
multiple processes associated with cell migration, such as embryogenesis and wound …

Glucocorticoids stimulate endolymphatic water reabsorption in inner ear through aquaporin 3 regulation

J Nevoux, S Viengchareun, I Lema, AL Lecoq… - … -European Journal of …, 2015 - Springer
Menière's disease, clinically characterized by fluctuating, recurrent, and invalidating vertigo,
hearing loss, and tinnitus, is linked to an increase in endolymph volume, the so-called …

Molecular aspects of aquaporins

S Li, C Li, W Wang - Vitamins and hormones, 2020 - Elsevier
Water can diffuse freely through the lipid bilayer at a limited rate or by water channel
proteins in a rapid speed. Aquaporins (AQPs) are a family of membrane water channel …

The Na+/H+ exchanger NHE1 localizes as clusters to cryptic lamellipodia and accelerates collective epithelial cell migration

HH Jensen, GA Pedersen, JJ Morgen… - The Journal of …, 2019 - Wiley Online Library
Key points Exogenous Na+/H+ exchanger 1 (NHE1) expression stimulated the collective
migration of epithelial cell sheets Stimulation with epidermal growth factor, a key …

AQP2 plasma membrane diffusion is altered by the degree of AQP2-S256 phosphorylation

EC Arnspang, FH Login, JS Koffman… - International Journal of …, 2016 - mdpi.com
Fine tuning of urine concentration occurs in the renal collecting duct in response to
circulating levels of arginine vasopressin (AVP). AVP stimulates intracellular cAMP …

Quantitative image mean squared displacement (iMSD) analysis of the dynamics of Aquaporin 2 within the membrane of live cells

YMZ Díaz, JL Kure, RA Grosso, C Andersen… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Nanodomains are a biological membrane phenomenon which have a large impact on
various cellular processes. They are often analysed by looking at the lateral dynamics of …

Classification and gene structure of aquaporins

L Xu, X Guo, W Wang, C Li - Aquaporins, 2023 - Springer
Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, 13 AQPs, distributed widely in …

Opposing effects of cAMP and T259 phosphorylation on plasma membrane diffusion of the water channel aquaporin-5 in madin-darby canine kidney cells

JS Koffman, EC Arnspang, S Marlar, LN Nejsum - PLoS One, 2015 - journals.plos.org
Aquaporin-5 (AQP5) facilitates passive water transport in glandular epithelia in response to
secretory stimuli via intracellular pathways involving calcium release, cAMP and protein …