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Mechanisms of HBV-induced hepatocellular carcinoma
M Levrero, J Zucman-Rossi - Journal of hepatology, 2016 - Elsevier
Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …
HBV DNA integration: molecular mechanisms and clinical implications
Chronic infection with the Hepatitis B Virus (HBV) is a major cause of liver-related morbidity
and mortality. One peculiar observation in cells infected with HBV (or with closely‑related …
and mortality. One peculiar observation in cells infected with HBV (or with closely‑related …
[HTML][HTML] Hepatitis B viral protein HBx and the molecular mechanisms modulating the hallmarks of hepatocellular carcinoma: a comprehensive review
With 296 million cases estimated worldwide, chronic hepatitis B virus (HBV) infection is the
most common risk factor for hepatocellular carcinoma (HCC). HBV-encoded oncogene X …
most common risk factor for hepatocellular carcinoma (HCC). HBV-encoded oncogene X …
Genomic medicine and implications for hepatocellular carcinoma prevention and therapy
The pathogenesis of hepatocellular carcinoma (HCC) is poorly understood, but recent
advances in genomics have increased our understanding of the mechanisms by which …
advances in genomics have increased our understanding of the mechanisms by which …
Hepatitis B virus genotypes and variants
CL Lin, JH Kao - Cold Spring Harbor …, 2015 - perspectivesinmedicine.cshlp.org
At least 10 hepatitis B virus (HBV) genotypes (A to J) with distinct geographic distributions
and several HBV mutants, including precore/core promoter mutations and pre-S/S deletion …
and several HBV mutants, including precore/core promoter mutations and pre-S/S deletion …
Natural history of acute and chronic hepatitis B: the role of HBV genotypes and mutants
CL Lin, JH Kao - Best Practice & Research Clinical Gastroenterology, 2017 - Elsevier
Molecular epidemiologic studies reveal remarkable differences in the geographical
distribution of hepatitis B virus (HBV) genotypes. The frequency of mutants among HBV …
distribution of hepatitis B virus (HBV) genotypes. The frequency of mutants among HBV …
Effect of antiviral treatment with nucleotide/nucleoside analogs on postoperative prognosis of hepatitis B virus–related hepatocellular carcinoma: a two-stage …
J Yin, N Li, Y Han, J Xue, Y Deng, J Shi… - Journal of clinical …, 2013 - ascopubs.org
Purpose Postoperative prognosis of hepatitis B virus (HBV)–related hepatocellular
carcinoma (HCC) is poor. The effect of nucleotide/nucleoside analog (NA) treatment on the …
carcinoma (HCC) is poor. The effect of nucleotide/nucleoside analog (NA) treatment on the …
Pathogenicity and virulence of Hepatitis B virus
Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …
an estimated 296 million people in the world that are chronically infected by this virus, and …
HBV-integration studies in the clinic: role in the natural history of infection
T Pollicino, G Caminiti - Viruses, 2021 - mdpi.com
Hepatitis B virus (HBV) infection is a major global health problem causing acute and chronic
liver disease that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). HBV …
liver disease that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). HBV …
Hepatitis B virus x protein in the pathogenesis of hepatitis B virus‐induced hepatocellular carcinoma
MC Kew - Journal of gastroenterology and hepatology, 2011 - Wiley Online Library
Currently available evidence supports a role for the hepatitis B virus (HBV) x gene and
protein in the pathogenesis of HBV‐induced hepatocellular carcinoma (HCC). HBx gene is …
protein in the pathogenesis of HBV‐induced hepatocellular carcinoma (HCC). HBx gene is …