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11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action
Glucocorticoid action on target tissues is determined by the density of “nuclear” receptors
and intracellular metabolism by the two isozymes of 11β-hydroxysteroid dehydrogenase …
and intracellular metabolism by the two isozymes of 11β-hydroxysteroid dehydrogenase …
Plastics derived endocrine‐disrupting compounds and their effects on early development
Despite the fact that the estrogenic effects of bisphenols were first described 80 years ago,
recent data about its potential negative impact on birth outcome parameters raises a strong …
recent data about its potential negative impact on birth outcome parameters raises a strong …
Prenatal stress and epigenetics
In utero exposure to environmental stress in both animals and humans could result in long-
term epigenome alterations which further lead to consequences for adaptation and …
term epigenome alterations which further lead to consequences for adaptation and …
Prenatal stress, glucocorticoids and the programming of adult disease
EC Cottrell, J Seckl - Frontiers in behavioral neuroscience, 2009 - frontiersin.org
Numerous clinical studies associate an adverse prenatal environment with the development
of cardio-metabolic disorders and neuroendocrine dysfunction, as well as an increased risk …
of cardio-metabolic disorders and neuroendocrine dysfunction, as well as an increased risk …
Mechanisms of disease: glucocorticoids, their placental metabolism and fetal'programming'of adult pathophysiology
Epidemiological evidence suggests that an adverse prenatal environment
permanently'programs' physiology and increases the risk of cardiovascular, metabolic …
permanently'programs' physiology and increases the risk of cardiovascular, metabolic …
Maternal psychosocial stress during pregnancy alters the epigenetic signature of the glucocorticoid receptor gene promoter in their offspring: a meta-analysis
Prenatal stress has been widely associated with a number of short-and long-term
pathological outcomes. Epigenetic mechanisms are thought to partially mediate these …
pathological outcomes. Epigenetic mechanisms are thought to partially mediate these …
Prenatal glucocorticoids and long-term programming
JR Seckl - European journal of endocrinology, 2004 - academic.oup.com
Epidemiological evidence suggests that low birth weight is associated with an increased risk
of cardiovascular, metabolic and neuroendocrine disorders in adult life. Glucocorticoid …
of cardiovascular, metabolic and neuroendocrine disorders in adult life. Glucocorticoid …
Endocrine regulation of human fetal growth: the role of the mother, placenta, and fetus
VE Murphy, R Smith, WB Giles, VL Clifton - Endocrine reviews, 2006 - academic.oup.com
The environment in which the fetus develops is critical for its survival and long-term health.
The regulation of normal human fetal growth involves many multidirectional interactions …
The regulation of normal human fetal growth involves many multidirectional interactions …
Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health
Environmental effects on the materno–foetal interaction determine birth outcomes that
predict health over the lifespan. Thus, maternal undernutrition or stress associate with low …
predict health over the lifespan. Thus, maternal undernutrition or stress associate with low …
A meta‐analysis of adverse perinatal outcomes in women with asthma
VE Murphy, JA Namazy, H Powell… - … Journal of Obstetrics …, 2011 - Wiley Online Library
Please cite this paper as: Murphy V, Namazy J, Powell H, Schatz M, Chambers C, Attia J,
Gibson P. A meta‐analysis of adverse perinatal outcomes in women with asthma. BJOG …
Gibson P. A meta‐analysis of adverse perinatal outcomes in women with asthma. BJOG …