Dendritic cells (DCs) exhibit a specialized antigen-presenting function and play crucial roles
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …

Cancer immunotherapies such as tumor vaccines, chimeric antigen receptor T cells and
immune checkpoint blockades, have attracted tremendous attention. Among them, tumor …

Malignant melanoma is one of the most aggressive forms of cancer and the leading cause of
death from skin tumors. Given the increased incidence of melanoma diagnoses in recent …

Tumor-infiltrating immune cells (TIICs) are critical players in the tumor microenvironment,
modulating cancer cell functions. TIICs are highly heterogenic and plastic and may either …

DCs play a pivotal role in orchestrating innate and adaptive antitumor immunity. Activated
DCs can produce large amounts of various proinflammatory cytokines, initiate T‐cell …

The tumor microenvironment (TME) plays a key role in promoting the initiation and
progression of tumors, leading to chemoradiotherapy resistance and immunotherapy failure …

Simple Summary With an overall 5-year survival of only 20% for advanced-stage ovarian
cancer patients, enduring and effective therapies are a highly unmet clinical need. Current …

The breast cancer tumor microenvironment (TME) is dynamic, with various immune and non-
immune cells interacting to regulate tumor progression and anti-tumor immunity. It is now …

Although the promise of cancer immunotherapy has been partially fulfilled with the
unprecedented clinical success of several immunotherapeutic interventions, some issues …

Simple Summary The tumor immune contexture plays a pivotal role for the clinical outcome
of cancer patients and the efficacy of various treatment modalities. Dendritic cells (DCs) …