Deep learning in electron microscopy

JM Ede - Machine Learning: Science and Technology, 2021 - iopscience.iop.org
Deep learning is transforming most areas of science and technology, including electron
microscopy. This review paper offers a practical perspective aimed at developers with …

Locating macromolecular assemblies in cells by 2D template matching with cisTEM

BA Lucas, BA Himes, L Xue, T Grant, J Mahamid… - Elife, 2021 - elifesciences.org
For a more complete understanding of molecular mechanisms, it is important to study
macromolecules and their assemblies in the broader context of the cell. This context can be …

CTFFIND5 provides improved insight into quality, tilt, and thickness of TEM samples

J Elferich, L Kong, X Zottig, N Grigorieff - eLife, 2024 - elifesciences.org
Images taken by transmission electron microscopes are usually affected by lens aberrations
and image defocus, among other factors. These distortions can be modeled in reciprocal …

Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes

ST Huber, E Sarajlic, R Hui**k, F Weis, WH Evers… - Elife, 2022 - elifesciences.org
Cryogenic electron microscopy has become an essential tool for structure determination of
biological macromolecules. In practice, the difficulty to reliably prepare samples with uniform …

[HTML][HTML] Microstructural evolution in laser melted boron alloyed Ti-6Al-4V

H Hizli, Z Zou, J Murray, A Clare, M Simonelli - Journal of Alloys and …, 2024 - Elsevier
Grain refinement in cast titanium alloys has been demonstrated through the addition of
boron (B) in hypoeutectic concentration. However, there is still a poor understanding of how …

Single-shot, coherent, pop-out 3D metrology

D Balakrishnan, SW Chee, Z Baraissov… - Communications …, 2023 - nature.com
Abstract Three-dimensional (3D) imaging of thin, extended specimens at nanometer
resolution is critical for applications in biology, materials science, advanced synthesis, and …

Best practice: setting up and operating a mid-sized cryo-EM facility

X Meng, I Ratnayake, ML Escobar Galvis… - Frontiers in Molecular …, 2023 - frontiersin.org
Ever since the resolution revolution in 2013, cryo-electron microscopy (cryo-EM) has
become a powerful methodology in structural biology that is especially suited to study the …

[PDF][PDF] Deep Learning in Electron Microscopy

M Learning - Advances in Electron Microscopy with Deep Learning, 2021 - arxiv.org
Deep learning is transforming most areas of science and technology, including electron
microscopy. This review paper offers a practical perspective aimed at developers with …