Advances in the physiology of gastric emptying
There have been many recent advances in the understanding of various aspects of the
physiology of gastric motility and gastric emptying. Earlier studies had discovered the …
physiology of gastric motility and gastric emptying. Earlier studies had discovered the …
The physiological control of eating: signals, neurons, and networks
AG Watts, SE Kanoski, G Sanchez-Watts… - Physiological …, 2022 - journals.physiology.org
During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …
Triple–hormone-receptor agonist retatrutide for obesity—a phase 2 trial
Background Retatrutide (LY3437943) is an agonist of the glucose-dependent insulinotropic
polypeptide, glucagon-like peptide 1, and glucagon receptors. Its dose–response …
polypeptide, glucagon-like peptide 1, and glucagon receptors. Its dose–response …
Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group …
Background According to current consensus guidelines for type 2 diabetes management,
bodyweight management is as important as attaining glycaemic targets. Retatrutide, a single …
bodyweight management is as important as attaining glycaemic targets. Retatrutide, a single …
Emerging role of the brain in the homeostatic regulation of energy and glucose metabolism
E Roh, DK Song, MS Kim - Experimental & molecular medicine, 2016 - nature.com
Accumulated evidence from genetic animal models suggests that the brain, particularly the
hypothalamus, has a key role in the homeostatic regulation of energy and glucose …
hypothalamus, has a key role in the homeostatic regulation of energy and glucose …
Nutritional ketosis for weight management and reversal of metabolic syndrome
Abstract Purpose of Review The goal of this paper is to review current literature on
nutritional ketosis within the context of weight management and metabolic syndrome …
nutritional ketosis within the context of weight management and metabolic syndrome …
The pathogenesis of obesity
SM Oussaada, KA Van Galen, MI Cooiman… - Metabolism, 2019 - Elsevier
Body fat mass increases when energy intake exceeds energy expenditure. In the long term,
a positive energy balance will result in obesity. The worldwide prevalence of obesity has …
a positive energy balance will result in obesity. The worldwide prevalence of obesity has …
Sex differences in the physiology of eating
L Asarian, N Geary - American Journal of Physiology …, 2013 - journals.physiology.org
Hypothalamic-pituitary-gonadal (HPG) axis function fundamentally affects the physiology of
eating. We review sex differences in the physiological and pathophysiological controls of …
eating. We review sex differences in the physiological and pathophysiological controls of …
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin …
Impaired insulin secretion is a hallmark of type 2 diabetes (T2D). Epigenetics may affect
disease susceptibility. To describe the human methylome in pancreatic islets and determine …
disease susceptibility. To describe the human methylome in pancreatic islets and determine …
Stress, eating and the reward system
TC Adam, ES Epel - Physiology & behavior, 2007 - Elsevier
An increasing number of people report concerns about the amount of stress in their life. At
the same time obesity is an escalating health problem worldwide. Evidence is accumulating …
the same time obesity is an escalating health problem worldwide. Evidence is accumulating …