[HTML][HTML] Pathophysiology of obesity and its associated diseases

X **, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Adolescent PCOS: a postpubertal central obesity syndrome

L Ibáñez, F de Zegher - Trends in molecular medicine, 2023 - cell.com
Adolescent polycystic ovary syndrome (PCOS) is a highly prevalent, reversible, endocrine-
metabolic mode essentially driven by ectopic fat, which, in turn, often results from a …

[HTML][HTML] The role of Glp-1 receptor agonists in insulin resistance with concomitant obesity treatment in polycystic ovary syndrome

K Bednarz, K Kowalczyk, M Cwynar, D Czapla… - International journal of …, 2022 - mdpi.com
Insulin resistance is documented in clamp studies in 75% of women with polycystic ovary
syndrome (PCOS). Although it is not included in the diagnostic criteria of PCOS, there is a …

[HTML][HTML] Metabolic syndrome and psoriasis: mechanisms and future directions

Y Hao, Y Zhu, S Zou, P Zhou, Y Hu, Q Zhao… - Frontiers in …, 2021 - frontiersin.org
Psoriasis is an immune-mediated systemic disease with associated comorbidities, including
metabolic syndrome (MetS) which contributes substantially to premature mortality in patients …

Nonalcoholic fatty liver disease: Current therapies and future perspectives in drug delivery

I Domingues, IA Leclercq, A Beloqui - Journal of Controlled Release, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) affects approximately 25% of the adult population
worldwide. This pathology can progress into end-stage liver disease with life-threatening …

Adipose–Muscle crosstalk in age-related metabolic disorders: The emerging roles of adipo-myokines

P Fang, Y She, M Yu, W Min, W Shang… - Ageing Research Reviews, 2023 - Elsevier
Obesity and type 2 diabetes account for a considerable proportion of the global burden of
age-related metabolic diseases. In age-related metabolic diseases, tissue crosstalk and …

Prevention of metabolic syndrome by phytochemicals and vitamin D

K Santa, Y Kumazawa, I Nagaoka - International Journal of Molecular …, 2023 - mdpi.com
In recent years, attention has focused on the roles of phytochemicals in fruits and vegetables
in maintaining and improving the intestinal environment and preventing metabolic …

Nanomodulator-mediated restructuring of adipose tissue immune microenvironments for antiobesity treatment

Q Li, J Byun, J Choi, J Park, J Lee, YK Oh - ACS nano, 2024 - ACS Publications
In obesity, the interactions between proinflammatory macrophages and adipocytes in white
adipose tissues are known to play a crucial role in disease progression by providing …

Adipokines as clinically relevant therapeutic targets in obesity

M Würfel, M Blüher, M Stumvoll, T Ebert, P Kovacs… - Biomedicines, 2023 - mdpi.com
Adipokines provide an outstanding role in the comprehensive etiology of obesity and may
link adipose tissue dysfunction to further metabolic and cardiovascular complications …

Maternal obesity and programming of metabolic syndrome in the offspring: searching for mechanisms in the adipocyte progenitor pool

TB Scheidl, AL Brightwell, SH Easson, JA Thompson - BMC medicine, 2023 - Springer
Background It is now understood that it is the quality rather than the absolute amount of
adipose tissue that confers risk for obesity-associated disease. Adipose-derived stem cells …