The eye is regarded as an immune privileged site. Since the presence of a vasculature
would impair vision, the vasculature of the eye is located outside of the central light path. As …

The retina is a complex tissue with multiple cell layers that are highly ordered. Its
sophisticated structure makes it especially sensitive to external or internal perturbations that …

Microglia, the immunocompetent cells of the central nervous system (CNS), act as
neuropathology sensors and are neuroprotective under physiological conditions. Microglia …

Glaucoma is an optic neuropathy that is characterized by the progressive degeneration of
the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible …

Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells
(RGCs) in the retina, often as a result of prolonged increases in intraocular pressure. We …

Glaucoma is a group of diseases characterized by progressive optic nerve degeneration that
results in visual field loss and irreversible blindness. A crucial element in the …

Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Glaucoma is a neurodegenerative disease of the retina characterized by the irreversible loss
of retinal ganglion cells (RGCs) leading to visual loss. Degeneration of RGCs and loss of …

Glaucoma is a common optic neuropathy with a complex etiology often linked to sensitivity to
intraocular pressure. Though the precise mechanisms that mediate or transduce this …

Due to their permanent and close proximity to neurons, glial cells perform essential tasks for
the normal physiology of the retina. Astrocytes and Müller cells (retinal macroglia) provide …