Diet and depression: exploring the biological mechanisms of action

W Marx, M Lane, M Hockey, H Aslam, M Berk… - Molecular …, 2021 - nature.com
The field of nutritional psychiatry has generated observational and efficacy data supporting a
role for healthy dietary patterns in depression onset and symptom management. To guide …

[HTML][HTML] Pathophysiology and current drug treatments for post-stroke depression: a review

D Frank, BF Gruenbaum, A Zlotnik… - International journal of …, 2022 - mdpi.com
Post-stroke depression (PSD) is a biopsychosocial disorder that affects individuals who
have suffered a stroke at any point. PSD has a 20 to 60 percent reported prevalence among …

Epigenetics and depression

S Penner-Goeke, EB Binder - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
The risk for major depression is both genetically and environmentally determined. It has
been proposed that epigenetic mechanisms could mediate the lasting increases in …

[HTML][HTML] Major depression and the biological hallmarks of aging

EC Lorenzo, GA Kuchel, CL Kuo, TE Moffitt… - Ageing research …, 2023 - Elsevier
Major depressive disorder (MDD) is characterized by psychological and physiological
manifestations contributing to the disease severity and outcome. In recent years, several …

Transcriptomic decoding of regional cortical vulnerability to major depressive disorder

J Zhu, X Chen, B Lu, XY Li, ZH Wang, LP Cao… - Communications …, 2024 - nature.com
Previous studies in small samples have identified inconsistent cortical abnormalities in
major depressive disorder (MDD). Despite genetic influences on MDD and the brain, it is …

Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

AV Sokolov, HB Schiöth - Translational Psychiatry, 2024 - nature.com
The causes of depression are complex, and the current diagnosis methods rely solely on
psychiatric evaluations with no incorporation of laboratory biomarkers in clinical practices …

Maternal hypertensive pregnancy disorders and mental disorders in children

M Lahti-Pulkkinen, P Girchenko, S Tuovinen… - …, 2020 - ahajournals.org
The associations of maternal hypertensive pregnancy disorders with offspring mental
disorders remain unclear. We examined whether maternal hypertensive disorders and …

Elevated BICD2 DNA methylation in blood of major depressive disorder patients and reduction of depressive-like behaviors in hippocampal Bicd2-knockdown mice

J **u, J Li, Z Liu, H Wei, C Zhu, R Han, Z Liu… - Proceedings of the …, 2022 - pnas.org
Major depressive disorder (MDD) is a prevalent and devastating mental illness. To date, the
diagnosis of MDD is largely dependent on clinical interviews and questionnaires and still …

The relationship between DNA methylation and antidepressant medications: a systematic review

LM Webb, KE Phillips, MC Ho, M Veldic… - International journal of …, 2020 - mdpi.com
Major depressive disorder (MDD) is the leading cause of disability worldwide and is
associated with high rates of suicide and medical comorbidities. Current antidepressant …

Genome-wide DNA methylation and gene expression analyses in monozygotic twins identify potential biomarkers of depression

W Wang, W Li, Y Wu, X Tian, H Duan, S Li… - Translational …, 2021 - nature.com
Depression is currently the leading cause of disability around the world. We conducted an
epigenome-wide association study (EWAS) in a sample of 58 depression score-discordant …