[HTML][HTML] Multi-layered genome defences in bacteria
Bacteria have evolved a variety of defence mechanisms to protect against mobile genetic
elements, including restriction-modification systems and CRISPR–Cas. In recent years …
elements, including restriction-modification systems and CRISPR–Cas. In recent years …
My host's enemy is my enemy: plasmids carrying CRISPR-Cas as a defence against phages
B Siedentop, D Rüegg… - Proceedings of the …, 2024 - royalsocietypublishing.org
Bacteria are infected by mobile genetic elements like plasmids and virulent phages, and
those infections significantly impact bacterial ecology and evolution. Recent discoveries …
those infections significantly impact bacterial ecology and evolution. Recent discoveries …
Molecular basis of foreign DNA recognition by BREX anti-phage immunity system
A Drobiazko, M Adams, M Skutel, P Kristina… - bioRxiv, 2024 - biorxiv.org
Anti-phage systems of the BREX (BacteRiophage EXclusion) superfamily rely on epigenetic
DNA methylation to discriminate between the host and invading DNA, but their mechanism …
DNA methylation to discriminate between the host and invading DNA, but their mechanism …
Correlation of Pseudomonas aeruginosa Phage Resistance with the Numbers and Types of Antiphage Systems
KA Burke, CD Urick, N Mzhavia, MP Nikolich… - International Journal of …, 2024 - mdpi.com
Phage therapeutics offer a potentially powerful approach for combating multidrug-resistant
bacterial infections. However, to be effective, phage therapy must overcome existing and …
bacterial infections. However, to be effective, phage therapy must overcome existing and …