Regulation and modulation of pH in the brain
M Chesler - Physiological reviews, 2003 - journals.physiology.org
Chesler, Mitchell. Regulation and Modulation of pH in the Brain. Physiol Rev 83: 1183-1221,
2003; 10.1152/physrev. 00010.2003.—The regulation of pH is a vital homeostatic function …
2003; 10.1152/physrev. 00010.2003.—The regulation of pH is a vital homeostatic function …
Ionic basis of GABAA receptor channel function in the nervous system
K Kaila - Progress in neurobiology, 1994 - Elsevier
The concept of nervous inhibition as a physiological phenomenon in its own right--not
merely as a lack of excitation--was central to a number of early theories on the integrative …
merely as a lack of excitation--was central to a number of early theories on the integrative …
Ionic Mechanisms of Neuronal Excitation by Inhibitory GABAA Receptors
KJ Staley, BL Soldo, WR Proctor - Science, 1995 - science.org
Gamma-aminobutyric acid A (GABAA) receptors are the principal mediators of synaptic
inhibition, and yet when intensely activated, dendritic GABAA receptors excite rather than …
inhibition, and yet when intensely activated, dendritic GABAA receptors excite rather than …
Interictal spikes in focal epileptogenesis
M De Curtis, G Avanzini - Progress in neurobiology, 2001 - Elsevier
Interictal electroencephalography (EEG) potentials in focal epilepsies are sustained by
synchronous paroxysmal membrane depolarization generated by assemblies of …
synchronous paroxysmal membrane depolarization generated by assemblies of …
Modulation of pH by neuronal activity
Although the requirement for a strict regulation of pH in the brain is frequently emphasized,
recent studies indicate that neuronal activity gives rise to significant changes in intraceUular …
recent studies indicate that neuronal activity gives rise to significant changes in intraceUular …
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis
Febrile seizures are frequent during early childhood, and prolonged (complex) febrile
seizures are associated with an increased susceptibility to temporal lobe epilepsy. The …
seizures are associated with an increased susceptibility to temporal lobe epilepsy. The …
pH regulation and proton signalling by glial cells
JW Deitmer, CR Rose - Progress in neurobiology, 1996 - Elsevier
The regulation of H+ in nervous systems is a function of several processes, including H+
buffering, intracellular H+ sequestering, C02 diffusion, carbonic anhydrase activity and …
buffering, intracellular H+ sequestering, C02 diffusion, carbonic anhydrase activity and …
ASIC‐like, proton‐activated currents in rat hippocampal neurons
A Baron, R Waldmann… - The Journal of physiology, 2002 - Wiley Online Library
The expression of mRNA for acid sensing ion channels (ASIC) subunits ASIC1a, ASIC2a
and ASIC2b has been reported in hippocampal neurons, but the presence of functional …
and ASIC2b has been reported in hippocampal neurons, but the presence of functional …
Pharmacological properties and H+ sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones.
1. N‐Methyl‐D‐aspartate (NMDA), alpha‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole
propionate (AMPA), and kainate receptor channels have been examined in rat cerebellar …
propionate (AMPA), and kainate receptor channels have been examined in rat cerebellar …
A furosemide-sensitive K+–Cl− cotransporter counteracts intracellular Cl− accumulation and depletion in cultured rat midbrain neurons
W Jarolimek, A Lewen, U Misgeld - Journal of Neuroscience, 1999 - Soc Neuroscience
Efficacy of postsynaptic inhibition through GABAAreceptors in the mammalian brain
depends on the maintenance of a Cl− gradient for hyperpolarizing Cl− currents. We have …
depends on the maintenance of a Cl− gradient for hyperpolarizing Cl− currents. We have …