Role of neuroinflammation in neurodegeneration development

W Zhang, D **ao, Q Mao, H **a - Signal transduction and targeted …, 2023 - nature.com
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …

Inflammation in Parkinson's disease: mechanisms and therapeutic implications

M Pajares, A I. Rojo, G Manda, L Boscá, A Cuadrado - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging

NE Propson, ER Roy, A Litvinchuk… - The Journal of …, 2021 - Am Soc Clin Investig
Dysfunction of immune and vascular systems has been implicated in aging and Alzheimer
disease; however, their interrelatedness remains poorly understood. The complement …

[HTML][HTML] Reducing neuroinflammation via therapeutic compounds and lifestyle to prevent or delay progression of Parkinson's disease

E Kip, LC Parr-Brownlie - Ageing Research Reviews, 2022 - Elsevier
Parkinson's disease (PD) is the second most common age-associated neurodegenerative
disorder and is characterised by progressive loss of dopamine neurons in the substantia …

Blood and cerebrospinal fluid biomarkers of inflammation in Parkinson's disease

M Zimmermann, K Brockmann - Journal of Parkinson's …, 2022 - content.iospress.com
Given the clear role of inflammation in the pathogenesis of Parkinson's disease (PD) and its
impact on incidence and phenotypical characteristics, this review provides an overview with …

Zika virus infection promotes local inflammation, cell adhesion molecule upregulation, and leukocyte recruitment at the blood-brain barrier

M Clé, C Desmetz, J Barthelemy, MF Martin… - MBio, 2020 - Am Soc Microbiol
The blood-brain barrier (BBB) largely prevents toxins and pathogens from accessing the
brain. Some viruses have the ability to cross this barrier and replicate in the central nervous …

Natural killer T-like cells: immunobiology and role in disease

JS Almeida, JM Casanova, M Santos-Rosa… - International Journal of …, 2023 - mdpi.com
CD56+ T cells are generally recognized as a distinct population of T cells and are
categorized as NKT-like cells. Although our understanding of NKT-like cells is far from …

Neuroprotective potential of cinnamon and its metabolites in Parkinson's disease: Mechanistic insights, limitations, and novel therapeutic opportunities

E Angelopoulou, YN Paudel, C Piperi… - Journal of biochemical …, 2021 - Wiley Online Library
Parkinson's disease (PD) is the most common neurodegenerative movement disorder with
obscure etiology and no disease‐modifying therapy to date. Hence, novel, safe, and low …

The role of CD56bright NK cells in neurodegenerative disorders

C Rodriguez-Mogeda, CMJ van Ansenwoude… - Journal of …, 2024 - Springer
Emerging evidence suggests a potential role for natural killer (NK) cells in
neurodegenerative diseases, such as multiple sclerosis, Alzheimer's disease, Parkinson's …

Advances in NURR1-regulated neuroinflammation associated with Parkinson's Disease

M Al-Nusaif, Y Lin, T Li, C Cheng, W Le - International Journal of …, 2022 - mdpi.com
Neuroinflammation plays a crucial role in the progression of neurodegenerative disorders,
particularly Parkinson's disease (PD). Glial cell activation and subsequent adaptive immune …