From many decades, S-heterocycles have maintained their status as an important part and
core of FDA approved drugs and medicinally active compounds. With exhaustive exploration …

Rheumatoid arthritis, arthrosis and gout, among other chronic inflammatory diseases are
public health problems and represent major therapeutic challenges. Non-steroidal anti …

Abstract The title compound 2-amino-4-(4-aminophenyl) thiophene-3-carbonitrile (AI3), was
synthesized and characterized experimentally by FT-IR, NMR and theoretically by quantum …

New cyano-acrylamide derivatives bearing the thiophene moiety were prepared and
rigorously characterized. Thus, the reaction of diethyl 5-(2-cyanoacetamido)-3 …

Eight Novel chalcones were synthesized and their structures were confirmed by different
spectral tools. All the prepared compounds were subjected to SRB cytotoxic screening …

A series of novel 1-(β-coumarinyl)-1-(β-indolyl)-1-(α-thiophenyl) trifluoroethane derivatives
5aaa-5hdb were prepared by one-pot reaction from 3-(trifluoroacetyl) coumarin with indole …

Quinoline ring system is extensively dispensed in natural products, especially in alkaloids.
Moreover, thieno [2, 3-b] quinolines have vast biological activities, including urea transporter …

Background: Bacterial infections are a growing problem worldwide causing morbidity and
mortality mainly in develo** countries. Moreover, the increased number of …

In this study, a new Schiff base derivative, 2-[(2-hydroxy-5-thiophen-2-yl-benzylidene)-
amino]-6-methyl-benzoic acid (5), which has a thiophene ring and N, O donor groups, was …

A novel series of 2‐cyano‐N‐(tetrahydrobenzo [b] thiophen‐2‐yl) acrylamide derivatives
were synthesized and their structures were confirmed using several spectral tools. All …