Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023 - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

Nanomaterials for cancer therapy: current progress and perspectives

Z Cheng, M Li, R Dey, Y Chen - Journal of hematology & oncology, 2021 - Springer
Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …

Evolution of drug delivery systems: From 1950 to 2020 and beyond

H Park, A Otte, K Park - Journal of Controlled Release, 2022 - Elsevier
Modern drug delivery technology began in 1952 with the advent of the Spansule® sustained-
release capsule technology, which can deliver a drug for 12 h after oral administration …

Engineering precision nanoparticles for drug delivery

MJ Mitchell, MM Billingsley, RM Haley… - Nature reviews drug …, 2021 - nature.com
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Cancer nanomedicine toward clinical translation: Obstacles, opportunities, and future prospects

P Zhang, Y **ao, X Sun, X Lin, S Koo, AV Yaremenko… - Med, 2023 - cell.com
With the integration of nanotechnology into the medical field at large, great strides have
been made in the development of nanomedicines for tackling different diseases, including …

Toxicity of nanoparticles in biomedical application: nanotoxicology

C Egbuna, VK Parmar, J Jeevanandam… - Journal of …, 2021 - Wiley Online Library
Nanoparticles are of great importance in development and research because of their
application in industries and biomedicine. The development of nanoparticles requires …

In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism

MM Billingsley, N Gong, AJ Mukalel, AS Thatte… - Small, 2024 - Wiley Online Library
With six therapies approved by the Food and Drug Association, chimeric antigen receptor
(CAR) T cells have reshaped cancer immunotherapy. However, these therapies rely on ex …

Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …

S Kansız, YM Elçin - Advances in Colloid and Interface Science, 2023 - Elsevier
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …

Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …