Human monocytes are divided in three major populations; classical (CD14+ CD16−), non-
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …

Ageing is a global burden. Increasing age is associated with increased incidence of
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …

The recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the
recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 …

The stromal compartment of the tumor microenvironment consists of a heterogeneous set of
tissue-resident and tumor-infiltrating cells, which are profoundly moulded by cancer cells. An …

Single-cell RNA sequencing (scRNA-seq) data are commonly affected by technical artifacts
known as" doublets," which limit cell throughput and lead to spurious biological conclusions …

Human monocytes have been grouped into classical (CD14++ CD16−), non-classical
(CD14dimCD16++), and intermediate (CD14++ CD16+) subsets. Documentation of normal …

Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …

Optimal vascular structure and function are essential for maintaining the physiological
functions of the cardiovascular system. Vascular remodelling involves changes in vessel …

Rheumatoid arthritis (RA) is a chronic systemic, autoimmune and inflammatory disease
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …

Given the importance of monocytes in pathogenesis of infectious and other inflammatory
disorders, delineating functional and phenotypic characterization of monocyte subsets has …