Background Retinitis pigmentosa (RP) is an inherited human retinal disorder that causes
progressive photoreceptor cell loss, leading to severe vision impairment or blindness …

Müller cells play a critical role in retinal metabolism and are among the first cells to
demonstrate metabolic changes in retinal stress or disease. The timing, extent, regulation …

Inherited mutations that lead to misfolding of the visual pigment rhodopsin (Rho) are a
prominent cause of photoreceptor neuron (PN) degeneration and blindness. How Rho …

Endocytosis of G-protein-coupled receptors (GPCRs) and associated channels contributes
to desensitization and adaptation of a variety of signaling cascades. In Drosophila …