Aerosol therapy is a key modality for drug delivery to the lungs of respiratory disease
patients. Aerosol therapy improves therapeutic effects by directly targeting diseased lung …

Introduction Aerosol therapy is commonly prescribed in the mechanically ventilated patient.
Jet nebulizers (JN) and vibrating mesh nebulizers (VMN) are the most common nebulizer …

The delivery of aerosols to mechanically ventilated patients presents unique challenges and
differs from inhaled drug delivery in spontaneously breathing patients in several respects …

Aerosolized medications are routinely used for the treatment of critically ill patients. This
paper reviews aerosol delivery devices with a focus on issues related to their performance in …

Inhaled medications are the mainstay of therapy for many pediatric pulmonary diseases.
Device and delivery technique selection is key to improving lung deposition of inhaled …

BACKGROUND: Optimization of factors affecting aerosol delivery during mechanical
ventilation in the pediatric population is important. We hypothesized that increasing the tidal …

In comparison with spontaneously breathing non-intubated subjects, intubated,
mechanically ventilated patients encounter various challenges, barriers, and opportunities in …

Although aerosol delivery through mechanical ventilators has been used to administer
various medications, little is known of administration with colistin. This in vitro evaluation …

Background Aerosol delivery via mechanical ventilation has been reported to vary
significantly among different intensive care units (ICU). The optimal technique for using each …

BACKGROUND: The present study tested a novel nebulizer and circuit that use breath
enhancement and breath actuation to minimize ventilator influences. The unique circuit …