[HTML][HTML] The role of insulin/IGF1 signalling in neurodevelopmental and neuropsychiatric disorders–evidence from human neuronal cell models

JM Réthelyi, K Vincze, D Schall, J Glennon… - … & Biobehavioral Reviews, 2023 - Elsevier
Insulin and insulin-like growth factor 1 (IGF1) signalling play a central role in the
development and maintenance of neurons in the brain, and in humans neurodevelopmental …

Phenotypes, mechanisms and therapeutics: insights from bipolar disorder GWAS findings

M Li, T Li, X ** brain in autism spectrum disorders
Y Vyas, JE Cheyne, K Lee, Y Jung… - Frontiers in …, 2021 - frontiersin.org
The SHANK family of proteins play critical structural and functional roles in the postsynaptic
density (PSD) at excitatory glutamatergic synapses. Through their multidomain structure they …

The PFC-LH-VTA pathway contributes to social deficits in IRSp53-mutant mice

YW Noh, Y Kim, S Lee, Y Kim, JJ Shin, H Kang… - Molecular …, 2023 - nature.com
Dopamine (DA) neurons in the ventral tegmental area (VTA) promote social brain functions
by releasing DA onto nucleus accumbens neurons, but it remains unclear how VTA neurons …

The emerging neuroimmune hypothesis of bipolar disorder: an updated overview of neuroimmune and microglial findings

A Chaves‐Filho, C Eyres, L Blöbaum… - Journal of …, 2024 - Wiley Online Library
Bipolar disorder (BD) is a severe and multifactorial disease, with onset usually in young
adulthood, which follows a progressive course throughout life. Replicated epidemiological …