Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs
SA Dilliard, DJ Siegwart - Nature Reviews Materials, 2023 - nature.com
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …
medicines that directly reprogramme the central dogma of biology to prevent and treat …
Targeting drugs to tumours using cell membrane-coated nanoparticles
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …
specific nature, causing harm to non-malignant tissues. Over the past several decades …
Design of therapeutic biomaterials to control inflammation
Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
[HTML][HTML] The limitless future of RNA therapeutics
Recent advances in the generation, purification and cellular delivery of RNA have enabled
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …
Toward nanotechnology-enabled approaches against the COVID-19 pandemic
The COVID-19 outbreak has fueled a global demand for effective diagnosis and treatment
as well as mitigation of the spread of infection, all through large-scale approaches such as …
as well as mitigation of the spread of infection, all through large-scale approaches such as …
[HTML][HTML] Recent progress in drug delivery
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …
desired tissues, organs, cells and subcellular organs for drug release and absorption …
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive
nanomedical tools because of their unique properties such as immune escape, long blood …
nanomedical tools because of their unique properties such as immune escape, long blood …
[HTML][HTML] Exosome theranostics: biology and translational medicine
C He, S Zheng, Y Luo, B Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …
Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis
Effectively activating macrophages against cancer is promising but challenging. In particular,
cancer cells express CD47, a 'don't eat me'signal that interacts with signal regulatory protein …
cancer cells express CD47, a 'don't eat me'signal that interacts with signal regulatory protein …