SARS-CoV-2 vaccination significantly reduces morbidity and mortality, but has less impact
on viral transmission rates, thus aiding viral evolution, and the longevity of vaccine-induced …

The use of autopsies in medicine has been declining. The COVID-19 pandemic has
documented and rejuvenated the importance of autopsies as a tool of modern medicine. In …

SARS-CoV-2 continues to evolve into variants of concern (VOC), with greatest variability in
the multidomain, entry-facilitating spike proteins. To recognize the significance of adaptive …

The mucosal immune system, as the most extensive peripheral immune network, serves as
the frontline defense against a myriad of microbial and dietary antigens. It is crucial in …

Current vaccines against SARS-CoV-2 substantially reduce mortality, but protection against
infection is less effective. Enhancing immunity in the respiratory tract, via mucosal …

Background Evidence for the impact of smoking on coronavirus disease 2019 (COVID-19) is
contradictory, and there is little research on va**. Here we provide greater clarity on …

Proteases represent common targets in combating infectious diseases, including COVID-19.
The 3-chymotrypsin-like protease (3CLpro) is a validated molecular target for COVID-19 …

Coronaviruses (CoVs) are a class of respiratory viruses with the potential to cause severe
respiratory diseases by infecting cells of the upper respiratory tract, bronchial epithelium …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the
associated coronavirus disease 2019 (COVID-19), which severely affect the respiratory …

Emergence of the betacoronavirus SARS-CoV-2 has resulted in a historic pandemic, with
millions of deaths worldwide. An unprecedented effort has been made by the medical …