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Best practices for single-cell analysis across modalities
Recent advances in single-cell technologies have enabled high-throughput molecular
profiling of cells across modalities and locations. Single-cell transcriptomics data can now …
profiling of cells across modalities and locations. Single-cell transcriptomics data can now …
[HTML][HTML] Revolutionizing medicinal chemistry: the application of artificial intelligence (AI) in early drug discovery
Artificial intelligence (AI) has permeated various sectors, including the pharmaceutical
industry and research, where it has been utilized to efficiently identify new chemical entities …
industry and research, where it has been utilized to efficiently identify new chemical entities …
g: Profiler—interoperable web service for functional enrichment analysis and gene identifier map** (2023 update)
Abstract g: Profiler is a reliable and up-to-date functional enrichment analysis tool that
supports various evidence types, identifier types and organisms. The toolset integrates many …
supports various evidence types, identifier types and organisms. The toolset integrates many …
Persistent complement dysregulation with signs of thromboinflammation in active Long Covid
Long Covid is a debilitating condition of unknown etiology. We performed multimodal
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …
The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
Much of the complexity within cells arises from functional and regulatory interactions among
proteins. The core of these interactions is increasingly known, but novel interactions …
proteins. The core of these interactions is increasingly known, but novel interactions …
Spatially resolved multiomics of human cardiac niches
The function of a cell is defined by its intrinsic characteristics and its niche: the tissue
microenvironment in which it dwells. Here we combine single-cell and spatial …
microenvironment in which it dwells. Here we combine single-cell and spatial …
JBrowse 2: a modular genome browser with views of synteny and structural variation
We present JBrowse 2, a general-purpose genome annotation browser offering enhanced
visualization of complex structural variation and evolutionary relationships. It retains core …
visualization of complex structural variation and evolutionary relationships. It retains core …
The reactome pathway knowledgebase 2024
Abstract The Reactome Knowledgebase (https://reactome. org), an Elixir and GCBR core
biological data resource, provides manually curated molecular details of a broad range of …
biological data resource, provides manually curated molecular details of a broad range of …
The IUPHAR/BPS guide to PHARMACOLOGY in 2024
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb; https://www.
guidetopharmacology. org) is an open-access, expert-curated, online database that …
guidetopharmacology. org) is an open-access, expert-curated, online database that …
LIPID MAPS: update to databases and tools for the lipidomics community
MJ Conroy, RM Andrews, S Andrews… - Nucleic Acids …, 2024 - academic.oup.com
Abstract LIPID MAPS (LIPID Metabolites and Pathways Strategy), www. lipidmaps. org,
provides a systematic and standardized approach to organizing lipid structural and …
provides a systematic and standardized approach to organizing lipid structural and …