Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped …

The first clinical applications of oxytocin (OT) were in obstetrics as a hormone to start and
speed up labor and to control postpartum hemorrhage. Discoveries in the 1960s and 1970s …

Despite intensive research into the etiopathogenesis of autism spectrum disorder (ASD),
limited progress has been achieved so far. Among the plethora of models seeking to clarify …

Animal and human studies have demonstrated that intranasal oxytocin (OT) can penetrate
the brain and induce cognitive, emotional, and behavioral changes, particularly in social …

The hypothalamus plays an important role in aging, but it remains unclear regarding the
underlying epigenetics and whether this hypothalamic basis can help address aging-related …

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders mainly
characterized by deficient sociability and repetitive behaviors. Effective treatment for the core …

Abstract Background Autism Spectrum Disorder (ASD) is a group of neurodevelopmental
disorders with higher incidence in males and is characterized by atypical verbal/nonverbal …

Despite promise in animal models, novel therapeutics consistently fail in clinical trials of
autism. Due to the heterogeneous nature of autism, treatment will likely only ameliorate …

Background and Purpose: No drugs targeting the core social features of autism spectrum
disorder (ASD) have been approved. Although clinical trials with oxytocin (OT) and …