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Molecular mechanisms of antibiotic resistance revisited
EM Darby, E Trampari, P Siasat, MS Gaya… - Nature Reviews …, 2023 - nature.com
Antibiotic resistance is a global health emergency, with resistance detected to all antibiotics
currently in clinical use and only a few novel drugs in the pipeline. Understanding the …
currently in clinical use and only a few novel drugs in the pipeline. Understanding the …
Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
S Qin, W ** soil resistome revealed by metagenomic analysis
Soil is recognized as the major reservoir of antibiotic resistance genes (ARGs), harboring
the most diverse naturally evolved ARGs on the planet. Multidrug resistance genes are a …
the most diverse naturally evolved ARGs on the planet. Multidrug resistance genes are a …
AcrAB− TolC, a major efflux pump in Gram negative bacteria: toward understanding its operation mechanism
S Jang - BMB reports, 2023 - pmc.ncbi.nlm.nih.gov
Antibiotic resistance (AR) is a silent pandemic that kills millions worldwide. Although the
development of new therapeutic agents against antibiotic resistance is in urgent demand …
development of new therapeutic agents against antibiotic resistance is in urgent demand …
Campylobacter jejuni in Poultry: Pathogenesis and Control Strategies
C. jejuni is the leading cause of human foodborne illness associated with poultry, beef, and
pork consumption. C. jejuni is highly prevalent in commercial poultry farms, where horizontal …
pork consumption. C. jejuni is highly prevalent in commercial poultry farms, where horizontal …
Allosteric drug transport mechanism of multidrug transporter AcrB
HK Tam, WE Foong, C Oswald, A Herrmann… - Nature …, 2021 - nature.com
Gram-negative bacteria maintain an intrinsic resistance mechanism against entry of noxious
compounds by utilizing highly efficient efflux pumps. The E. coli AcrAB-TolC drug efflux …
compounds by utilizing highly efficient efflux pumps. The E. coli AcrAB-TolC drug efflux …
Ever-adapting RND efflux pumps in gram-negative multidrug-resistant pathogens: a race against time
The rise in multidrug resistance (MDR) is one of the greatest threats to human health
worldwide. MDR in bacterial pathogens is a major challenge in healthcare, as bacterial …
worldwide. MDR in bacterial pathogens is a major challenge in healthcare, as bacterial …
Bdellovibrio predation cycle characterized at nanometre-scale resolution with cryo-electron tomography
Bdellovibrio bacteriovorus is a microbial predator that offers promise as a living antibiotic for
its ability to kill Gram-negative bacteria, including human pathogens. Even after six decades …
its ability to kill Gram-negative bacteria, including human pathogens. Even after six decades …