Krüppel-like factor 4 (KLF4): What we currently know
AM Ghaleb, VW Yang - Gene, 2017 - Elsevier
Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing
transcription factor that regulates diverse cellular processes such as cell growth …
transcription factor that regulates diverse cellular processes such as cell growth …
KLF4 transcription factor in tumorigenesis
Z He, J He, K **e - Cell death discovery, 2023 - nature.com
Krüppel-like transcriptional factor is important in maintaining cellular functions. Deletion of
Krüppel-like transcriptional factor usually causes abnormal embryonic development and …
Krüppel-like transcriptional factor usually causes abnormal embryonic development and …
Epithelial to mesenchymal transition: a mechanism that fuels cancer radio/chemoresistance
J Dudás, A Ladányi, J Ingruber, TB Steinbichler… - Cells, 2020 - mdpi.com
Epithelial to mesenchymal transition (EMT) contributes to tumor progression, cancer cell
invasion, and therapy resistance. EMT is regulated by transcription factors such as the …
invasion, and therapy resistance. EMT is regulated by transcription factors such as the …
CircPLEKHM3 acts as a tumor suppressor through regulation of the miR-9/BRCA1/DNAJB6/KLF4/AKT1 axis in ovarian cancer
L Zhang, Q Zhou, Q Qiu, L Hou, M Wu, J Li, X Li, B Lu… - Molecular Cancer, 2019 - Springer
Background Emerging evidence has shown that circular RNAs (circRNAs) play essential
roles in cancer biology and are potential biomarkers and targets for cancer therapy …
roles in cancer biology and are potential biomarkers and targets for cancer therapy …
Harnessing function of EMT in cancer drug resistance: a metastasis regulator determines chemotherapy response
Epithelial-mesenchymal transition (EMT) is a complicated molecular process that governs
cellular shape and function changes throughout tissue development and embryogenesis. In …
cellular shape and function changes throughout tissue development and embryogenesis. In …
The role of cytokines in epithelial–mesenchymal transition in gynaecological cancers: a systematic review
I Ray, A Michael, LB Meira, PE Ellis - Cells, 2023 - mdpi.com
Chronic inflammation has been closely linked to the development and progression of
various cancers. The epithelial–mesenchymal transition (EMT) is a process involving the …
various cancers. The epithelial–mesenchymal transition (EMT) is a process involving the …
Epithelial-to-mesenchymal transition in the female reproductive tract: from normal functioning to disease pathology
O Bilyk, M Coatham, M Jewer, LM Postovit - Frontiers in oncology, 2017 - frontiersin.org
Epithelial-to-mesenchymal transition (EMT) is a physiological process that is vital throughout
the human lifespan. In addition to contributing to the development of various tissues within …
the human lifespan. In addition to contributing to the development of various tissues within …
[HTML][HTML] Exosomes as mediators of platinum resistance in ovarian cancer
Exosomes have been implicated in the cell-cell transfer of oncogenic proteins and genetic
material. We speculated this may be one mechanism by which an intrinsically platinum …
material. We speculated this may be one mechanism by which an intrinsically platinum …
[HTML][HTML] Knockout of MTF1 inhibits the epithelial to mesenchymal transition in ovarian cancer cells
Due to peritoneal metastasis and frequent recurrence, ovarian cancer has the highest
mortality among gynecological cancers. Epithelial to mesenchymal transition (EMT) …
mortality among gynecological cancers. Epithelial to mesenchymal transition (EMT) …
miR-203 inhibits ovarian tumor metastasis by targeting BIRC5 and attenuating the TGFβ pathway
B Wang, X Li, G Zhao, H Yan, P Dong, H Watari… - Journal of Experimental …, 2018 - Springer
Background We previously reported that miR-203 functions as a tumor suppressor in
ovarian cancer cells by directly targeting transcription factor Snai2 and inhibiting epithelial to …
ovarian cancer cells by directly targeting transcription factor Snai2 and inhibiting epithelial to …