Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies characterized
by the degeneration of rod photoreceptors, followed by the degeneration of cone …

Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct
lesions that occur in the subretinal space. Over the past three decades, their presence in …

Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …

Recent advancements in artificial intelligence (AI) herald transformative potentials for
resha** glaucoma clinical management, improving screening efficacy, sharpening …

Long-term use of hydroxychloroquine can cause retinopathy, which may result in severe and
progressive visual loss. In the past decade, hydroxychloroquine use has markedly increased …

A progression sequence for age-related macular degeneration onset may be determinable
with consensus neuroanatomical nomenclature augmented by drusen biology and eye …

Regulatory approval of the first two therapeutic substances for the management of
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …

Disease mechanisms have become better understood in previously incurable forms of early-
onset severe retinal dystrophy, such as Leber congenital amaurosis (LCA). This has led to …

Background Neurological and ophthalmological neurodegenerative diseases in large part
share underlying biology and pathophysiology. Despite extensive preclinical research on …

PURPOSE To investigate the natural disease course of retinal dystrophies associated with
crumbs cell polarity complex component 1 (CRB1) and identify clinical end points for future …