Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

Mucins are large glycoproteins that are ubiquitous in the animal kingdom. Mucins coat the
surfaces of many cell types and can be secreted to form mucus gels that assume important …

The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or-stimulated
lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the …

IgG antibodies (Abs) and fragments of IgG Abs are becoming major biotherapeutics to treat
an assortment of human diseases. Commonly prepared fragments of IgGs include Fc, Fab …

The bile salt-dependent lipase (BSDL, EC 1.1. 1.13), also referred to as cholesterol
esterase, carboxyl ester hydrolase, carboxyl ester lipase [1] or lysophospholipase [2], is …

Saliva functions in innate immunity of the oral cavity, protecting against demineralization of
teeth (ie dental caries), a highly prevalent infectious disease associated with Streptococcus …

Maturity-onset diabetes of the young, type 8 (MODY8) is characterized by a syndrome of
autosomal dominantly inherited diabetes and exocrine pancreatic dysfunction. It is caused …

Variable number of tandem repeat (VNTR) sequences in the genome can have functional
consequences that contribute to human disease. This is the case for the CEL gene, which is …

Introduction Mutations of CEL gene were first reported to cause a new type of maturity-onset
diabetes of the young (MODY) denoted as MODY8 and then were also found in patients with …

Dictyostelium produces spores at the end of its developmental cycle to propagate the
lineage. The spore coat is an essential feature of spore biology contributing a …