Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018‏ - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Extracellular vesicles: the next generation of biomarkers for liquid biopsy-based prostate cancer diagnosis

B Pang, Y Zhu, J Ni, J Thompson, D Malouf… - …, 2020‏ - pmc.ncbi.nlm.nih.gov
Prostate cancer (PCa) is a leading cause of cancer death for males in western countries.
The current gold standard for PCa diagnosis-template needle biopsies-often does not …

Advanced functional nanomaterials for theranostics

H Huang, JF Lovell - Advanced functional materials, 2017‏ - Wiley Online Library
Nanoscale materials have been explored extensively as agents for therapeutic and
diagnostic (ie, theranostic) applications. Research efforts have shifted from exploring new …

Nuclear data for production and medical application of radionuclides: present status and future needs

SM Qaim - Nuclear medicine and biology, 2017‏ - Elsevier
Introduction The significance of nuclear data in the choice and medical application of a
radionuclide is considered: the decay data determine its suitability for organ imaging or …

Casp3/7-Instructed Intracellular Aggregation of Fe3O4 Nanoparticles Enhances T2 MR Imaging of Tumor Apoptosis

Y Yuan, Z Ding, J Qian, J Zhang, J Xu, X Dong… - Nano …, 2016‏ - ACS Publications
Large magnetic nanoparticles or aggregates are advantageous in their magnetic resonance
properties over ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles (NPs), but …

Unprecedented Kinetic Inertness for a Mn2+‐Bispidine Chelate: A Novel Structural Entry for Mn2+‐Based Imaging Agents

D Ndiaye, M Sy, A Pallier, S Même… - Angewandte Chemie …, 2020‏ - Wiley Online Library
The search for more biocompatible alternatives to Gd3+‐based MRI agents, and the interest
in 52Mn for PET imaging call for ligands that form inert Mn2+ chelates. Given the labile …

Improving the In Vivo Stability of [52Mn]Mn(II) Complexes with 18-Membered Macrocyclic Chelators for PET Imaging

C Harriswangler, JM Omweri, S Saini… - Journal of Medicinal …, 2024‏ - ACS Publications
We report the [natMn/52Mn] Mn (II) complexes of the macrocyclic chelators PYAN [3, 6, 10,
13-tetraaza-1, 8 (2, 6)-dipyridinacyclotetradecaphane] and CHXPYAN [(41 R, 42 R, 101 R …

Nanoparticle-based cell trackers for biomedical applications

JS Ni, Y Li, W Yue, B Liu, K Li - Theranostics, 2020‏ - pmc.ncbi.nlm.nih.gov
The continuous or real-time tracking of biological processes using biocompatible contrast
agents over a certain period of time is vital for precise diagnosis and treatment, such as …

Novel Preparation Methods of 52Mn for ImmunoPET Imaging

SA Graves, R Hernandez, J Fonslet… - Bioconjugate …, 2015‏ - ACS Publications
52Mn (t 1/2= 5.59 d, β+= 29.6%, E βave= 0.24 MeV) shows promise in positron emission
tomography (PET) and in dual-modality manganese-enhanced magnetic resonance …

[HTML][HTML] Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography

WM Arif, PH Elsinga, C Gasca-Salas, M Versluis… - Journal of controlled …, 2020‏ - Elsevier
Focused ultrasound (FUS) is a minimally-invasive technology used for treatment of many
diseases, including diseases related to the colon, uterus, prostate, and brain. Although it has …