Purpose Insomnia is problematic for older adults. After behavioral modifications fail to show
adequate response, pharmacologic options are used. The pharmacokinetics of agents used …

Abstract The Movement Disorder Society (MDS) Task Force on Evidence‐Based Medicine
(EBM) Review of Treatments for Parkinson's Disease (PD) was first published in 2002 and …

Abstract Study Objective: To compare cognitive behavioral therapy for insomnia (CBT-I)+
antidepressant medication (AD) against treatments that target solely depression or solely …

There are numerous pyrazine and phenazine compounds that demonstrate biological
activities relevant to the treatment of disease. In this review, we discuss pyrazine and …

Pyrazine is a six-membered heterocyclic ring containing nitrogen, and many of its
derivatives are biologically active compounds. References have been downloaded through …

A novel series of Ni (II)-Schiff base complexes were synthesized from five hydrazide
derivatives. All new synthesizes were fully characterized applying analytical and spectral …

A facile, efficient and general synthetic method for iodopyridines is described. When treated
with molecular iodine in the presence of sodium bicarbonate, N-propargylic β-enaminones …

Because of proven efficacy, reduced side effects, and less concern about addiction, non-
benzodiazepine receptor agonists (non-BzRA) have become the most commonly prescribed …

Study objective In this study, we performed a systematic review and meta-analysis of double-
blind, randomized, placebo-controlled trials to evaluate the efficacy and safety of …

A facile and efficient synthetic route to arylpyridines is reported. When heated with boronic
acids in the presence of 5 mol% PdCl 2 (PPh 3) 2 and KHCO 3 in 4: 1 DMF/H 2 O solution at …