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Recent advances in user-friendly computational tools to engineer protein function
Progress in technology and algorithms throughout the past decade has transformed the field
of protein design and engineering. Computational approaches have become well-engrained …
of protein design and engineering. Computational approaches have become well-engrained …
Ca2+ binding to F‐ATP synthase β subunit triggers the mitochondrial permeability transition
F‐ATP synthases convert the electrochemical energy of the H+ gradient into the chemical
energy of ATP with remarkable efficiency. Mitochondrial F‐ATP synthases can also undergo …
energy of ATP with remarkable efficiency. Mitochondrial F‐ATP synthases can also undergo …
In silico approaches to investigate enzyme immobilization: a comprehensive systematic review
F Barati, F Hosseini, R Vafaee, Z Sabouri… - Physical Chemistry …, 2024 - pubs.rsc.org
Enzymes are popular catalysts with many applications, especially in industry. Biocatalyst
usage on a large scale is facing some limitations, such as low operational stability, low …
usage on a large scale is facing some limitations, such as low operational stability, low …
[HTML][HTML] Omicron coronavirus: pH-dependent electrostatic potential and energy of association of spike protein to ACE2 receptor
SH Hristova, AM Zhivkov - Viruses, 2023 - mdpi.com
The association of the S-protein of the SARS-CoV-2 beta coronavirus to ACE2 receptors of
the human epithelial cells determines its contagiousness and pathogenicity. We computed …
the human epithelial cells determines its contagiousness and pathogenicity. We computed …
Potyvirus virion structure shows conserved protein fold and RNA binding site in ssRNA viruses
M Zamora, E Méndez-López, X Agirrezabala… - Science …, 2017 - science.org
Potyviruses constitute the second largest genus of plant viruses and cause important
economic losses in a large variety of crops; however, the atomic structure of their particles …
economic losses in a large variety of crops; however, the atomic structure of their particles …
Bioorthogonal catalytic activation of platinum and ruthenium anticancer complexes by FAD and flavoproteins
S Alonso‐de Castro, AL Cortajarena… - Angewandte …, 2018 - Wiley Online Library
Recent advances in bioorthogonal catalysis promise to deliver new chemical tools for
performing chemoselective transformations in complex biological environments. Herein, we …
performing chemoselective transformations in complex biological environments. Herein, we …
Intraparticle macromolecular migration alters the structure and function of proteins reversibly immobilized on porous microbeads
While migration of reversibly immobilized proteins across the volume of supports is
investigated in conditions where an external force is applied or under fluid flow conditions …
investigated in conditions where an external force is applied or under fluid flow conditions …
Structure of Turnip mosaic virus and its viral-like particles
Turnip mosaic virus (TuMV), a potyvirus, is a flexible filamentous plant virus that displays a
helical arrangement of coat protein copies (CPs) bound to the ssRNA genome. TuMV is a …
helical arrangement of coat protein copies (CPs) bound to the ssRNA genome. TuMV is a …
Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin
PP Mangione, G Esposito, A Relini, S Raimondi… - Journal of Biological …, 2013 - jbc.org
Systemic amyloidosis is a fatal disease caused by misfolding of native globular proteins,
which then aggregate extracellularly as insoluble fibrils, damaging the structure and function …
which then aggregate extracellularly as insoluble fibrils, damaging the structure and function …
PUFFFIN: an ultra-bright, customisable, single-plasmid system for labelling cell neighbourhoods
Cell communication coordinates developmental processes, maintains homeostasis, and
contributes to disease. Therefore, understanding the relationship between cells in a shared …
contributes to disease. Therefore, understanding the relationship between cells in a shared …