Multiple studies suggested using different miRNAs as biomarkers for prognosis of
hepatocellular carcinoma (HCC). We aimed to assemble a miRNA expression database …

Abstract Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor
with many important functions in the biology of normal and transformed cells. Its regulation is …

Background Survival analysis is a cornerstone of medical research, enabling the
assessment of clinical outcomes for disease progression and treatment efficiency. Despite …

Pancreatic ductal adenocarcinoma (PDAC) remains a lethal malignancy with an
immunosuppressive microenvironment that is resistant to most therapies. IL17 is involved in …

Systemic therapy of breast cancer can include chemotherapy, hormonal therapy and
targeted therapy. Prognostic biomarkers are able to predict survival and predictive …

The oncofetal mRNA-binding protein IGF2BP1 and the transcriptional regulator SRF
modulate gene expression in cancer. In cancer cells, we demonstrate that IGF2BP1 …

Copper plays pivotal roles in metabolic homoeostasis, but its potential role in human
tumorigenesis is not well defined. Here, it is revealed that copper activates the …

Background: Layilin (LAYN) is a critical gene that regulates T cell function. However, the
correlations of LAYN to prognosis and tumor-infiltrating lymphocytes in different cancers …

Background Breast cancer angiogenesis is key for metastasis and predicts a poor
prognosis. Angiotensin-converting enzyme 2 (ACE2), as a member of the renin-angiotensin …

Although it is established that fatty acid (FA) synthesis supports anabolic growth in cancer,
the role of exogenous FA uptake remains elusive. Here we show that, during acquisition of …