A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health

M Rodriguez-Concepcion, J Avalos, ML Bonet… - Progress in lipid …, 2018 - Elsevier
Carotenoids are lipophilic isoprenoid compounds synthesized by all photosynthetic
organisms and some non-photosynthetic prokaryotes and fungi. With some notable …

Carotenoid biofortification in crop plants: citius, altius, fortius

X Zheng, G Giuliano, S Al-Babili - … et Biophysica Acta (BBA)-Molecular and …, 2020 - Elsevier
Carotenoids are indispensable for human health, required as precursors of vitamin A and
efficient antioxidants. However, these plant pigments that play a vital role in photosynthesis …

Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants

Z Xu, X Pu, R Gao, OC Demurtas, SJ Fleck, M Richter… - BMC biology, 2020 - Springer
Background Plants have evolved a panoply of specialized metabolites that increase their
environmental fitness. Two examples are caffeine, a purine psychotropic alkaloid, and …

The honeysuckle genome provides insight into the molecular mechanism of carotenoid metabolism underlying dynamic flower coloration

X Pu, Z Li, Y Tian, R Gao, L Hao, Y Hu, C He… - New …, 2020 - Wiley Online Library
Lonicera japonica is a widespread member of the Caprifoliaceae (honeysuckle) family
utilized in traditional medical practices. This twining vine honeysuckle also is a much‐sought …

Gardenia carotenoid cleavage dioxygenase 4a is an efficient tool for biotechnological production of crocins in green and non‐green plant tissues

X Zheng, J Mi, A Balakrishna, KX Liew… - Plant Biotechnology …, 2022 - Wiley Online Library
Crocins are beneficial antioxidants and potential chemotherapeutics that give raise, together
with picrocrocin, to the colour and taste of saffron, the most expensive spice, respectively …

Regulation of carotenoid degradation and production of apocarotenoids in natural and engineered organisms

MH Liang, YJ He, DM Liu, JG Jiang - Critical Reviews in …, 2021 - Taylor & Francis
Carotenoids are important precursors of a wide range of apocarotenoids with their functions
including: hormones, pigments, retinoids, volatiles, and signals, which can be used in the …

Exploring the diversity and regulation of apocarotenoid metabolic pathways in plants

X Zheng, Y Yang, S Al-Babili - Frontiers in Plant Science, 2021 - frontiersin.org
In plants, carotenoids are subjected to enzyme-catalyzed oxidative cleavage reactions as
well as to non-enzymatic degradation processes, which produce various carbonyl products …

[HTML][HTML] Efficient production of saffron crocins and picrocrocin in Nicotiana benthamiana using a virus-driven system

M Martí, G Diretto, V Aragonés, S Frusciante… - Metabolic …, 2020 - Elsevier
Crocins and picrocrocin are glycosylated apocarotenoids responsible, respectively, for the
color and the unique taste of the saffron spice, known as red gold due to its high price …

Natural overexpression of CAROTENOID CLEAVAGE DIOXYGENASE 4 in tomato alters carotenoid flux

HJ Yoo, MY Chung, HA Lee, SB Lee… - Plant …, 2023 - academic.oup.com
Carotenoids and apocarotenoids function as pigments and flavor volatiles in plants that
enhance consumer appeal and offer health benefits. Tomato (Solanum lycopersicum.) fruit …

A New Glycosyltransferase Enzyme from Family 91, UGT91P3, Is Responsible for the Final Glucosylation Step of Crocins in Saffron (Crocus sativus L.)

AJ López-Jimenez, S Frusciante, E Niza… - International Journal of …, 2021 - mdpi.com
Crocetin is an apocarotenoid formed from the oxidative cleavage of zeaxanthin, by the
carotenoid cleavage enzymes CCD2 (in Crocus species) and specific CCD4 enzymes in …