Nephrolithiasis in children is a painful and costly disease that may also have detrimental
long-term effects on kidney function. Recent data provide evidence that the incidence of …

Pediatric urolithiasis is an endemic disease in certain parts of the world, namely Turkey and
the Far East. As a recurrent pathology which may reveal functional as well and morphologic …

Kidney stone disease is a common condition. To search for sequence variants conferring
risk of kidney stones, we conducted a genome-wide association study in 3,773 cases and …

The evaluation of metabolic risk factor in children with renal stone disease is the basis of
medical treatment aimed at preventing recurrent stone events and the growth of preexisting …

High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse
model of Dent's disease. Background Dent's disease, an X-linked renal tubular disorder, is …

Background The prevalence of kidney stones in children has significantly increased in the
past few decades, with concomitant increased morbidity and healthcare costs worldwide …

PURPOSE: We analyzed the metabolic abnormalities in children with urolithiasis, and the
relationship between diet and hypocitraturia. MATERIALS AND METHODS: A single center …

Background An increase in the incidence of kidney stone disease has been reported for all
age groups worldwide. To examine this trend, we conducted a nationwide study of the …

Laboratory evaluation is a major component in the assessment for renal disease in children.
Because clinical examination rarely provides sufficient information to establish a diagnosis …

Background The incidence of nephrolithiasis in children and adolescents is increasing and
appears to double every 10 years. The most important role of the pediatric nephrologist is to …