Sex differences are reported in hippocampal plasticity, cognition, and in a number of
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …

Modern head-mounted displays (HMDs) are a promising technology. Thanks to their
affordable cost and versatility, HMDs are gaining attention from different sectors. However …

Suicidality is exceedingly prevalent in pain patients. Although the pathophysiology of this
link remains unclear, it may be potentially related to the partial congruence of physical and …

Anomalies in fear learning, such as failure to inhibit fear to safe stimuli, lead to sustained
anxiety, which in turn may augment pain. In the same vein, stimulus generalization is …

Recent neuropsychological theories emphasize the influence of maladaptive learning and
memory processes on pain perception. However, the precise relationship between these …

In chronic musculoskeletal pain, avoidance behavior is a prominent behavioral
characteristic that can manifest itself in various ways. It is also considered a crucial …

Prominent clinical models of chronic pain propose a fundamental role of classical
conditioning in the development of pain-related disability. If classical conditioning is key to …

Highlights•Men and women differ in their ability to acquire and to extinguish fear.•Sex
hormones play a critical role in the modulation of fear conditioning processes.•Low estrogen …

This functional magnetic resonance imaging study addressed similarities and differences in
behavioral and neural responses to experimental visceral compared with somatic pain …

Current fear-avoidance models consider pain-related fear as a crucial factor in the
development of chronic pain. However, pain-related fear often occurs in a context of …