Sequencing of nucleic acids with nanopores has emerged as a powerful tool offering rapid
readout, high accuracy, low cost and portability. This label-free method for sequencing at the …

The recurring instances of infectious disease outbreaks, coupled with complications such as
comorbidity challenges and antibiotic resistance, consistently underscore the limitations …

We report on single-molecule nanopore sensing combined with position-encoded DNA
molecular probes, with chemistry tuned to simultaneously identify various antigen proteins …

Protein sequencing and the identification of post-translational modifications are key to
understanding cellular signalling pathways and metabolic processes in health and disease …

Viral outbreaks can cause widespread disruption, creating the need for diagnostic tools that
provide high performance and sample versatility at the point of use with moderate …

The DNA frame structure as a natural shell to stably shield the sequence-templated Ag
nanocluster core (cs AgNC) is intriguing yet challenging for applicable fluorescence …

Transcription, a critical process in molecular biology, has found many applications in RNA
synthesis, including mRNA vaccines and RNA therapeutics. However, current RNA …

RNA is a key biochemical marker, yet its chemical instability and complex secondary
structure hamper its integration into DNA nanotechnology-based sensing platforms. Relying …

Multiplexed nucleic acid sensing methods with high specificity are vital for clinical
diagnostics and infectious disease control, especially in the postpandemic era. Nanopore …

Nanopore analysis relies on ensemble averaging of translocation signals obtained from
numerous molecules, requiring a relatively high sample concentration and a long …