A review on the green synthesis of benzimidazole derivatives and their pharmacological activities
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …
Second and third-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumour activity
GV Suárez-Moreno, D Hernández-Romero… - Coordination Chemistry …, 2022 - Elsevier
The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …
some isolated reports about the therapeutic importance of metals and their compounds in …
Molecular superoxide radical photogeneration in cancer cells by dipyridophenazine iridium (III) complexes
V Novohradsky, G Vigueras, J Pracharova… - Inorganic Chemistry …, 2019 - pubs.rsc.org
The phototoxicity in cancer cells of three series of octahedral Ir (III) complexes of the general
formula [Ir (C^ N) 2 (N^ N)][PF6], where the N^ N ligand is dipyrido [3, 2-a: 2′, 3′-c] …
formula [Ir (C^ N) 2 (N^ N)][PF6], where the N^ N ligand is dipyrido [3, 2-a: 2′, 3′-c] …
[HTML][HTML] A 2-(benzothiazol-2-yl)-phenolato platinum (II) complex as potential photosensitizer for combating bacterial infections in lung cancer chemotherapy
Cancer and antibiotic resistance are two global health threats that usually hamper clinical
chemotherapeutic efficacy. Particularly for lung cancer, bacterial infections frequently arise …
chemotherapeutic efficacy. Particularly for lung cancer, bacterial infections frequently arise …
Exploring the Potential of Metal‐Based Candidate Drugs as Modulators of the Cytoskeleton
Y Borutzki, L Skos, C Gerner… - …, 2023 - Wiley Online Library
During recent years, accumulating evidence suggested that metal‐based candidate drugs
are promising modulators of cytoskeletal and cytoskeleton‐associated proteins. This was …
are promising modulators of cytoskeletal and cytoskeleton‐associated proteins. This was …
Cyclometalated osmium compounds and beyond: Synthesis, properties, applications
R Cerón-Camacho, MA Roque-Ramires, AD Ryabov… - Molecules, 2021 - mdpi.com
The synthesis of cyclometalated osmium complexes is usually more complicated than of
other transition metals such as Ni, Pd, Pt, Rh, where cyclometalation reactions readily occur …
other transition metals such as Ni, Pd, Pt, Rh, where cyclometalation reactions readily occur …
Fast Hydrolysis and Strongly Basic Water Adducts Lead to Potent Os (II) Half-Sandwich Anticancer Complexes
S Infante-Tadeo, V Rodríguez-Fanjul… - Inorganic …, 2022 - ACS Publications
Complexes of the formula [Os (η6-arene)(C, N-phenylpyridine) Z](where Z is chlorido or a
tethered oxygen) undergo very fast Os–Z hydrolysis (< 5 min), and the high basicity of the …
tethered oxygen) undergo very fast Os–Z hydrolysis (< 5 min), and the high basicity of the …
Novel organo-osmium (ii) proteosynthesis inhibitors active against human ovarian cancer cells reduce gonad tumor growth in Caenorhabditis elegans
E Ortega, FJ Ballester, A Hernández-García… - Inorganic Chemistry …, 2021 - pubs.rsc.org
This work reports the synthesis and characterization of some novel osmium (II) complexes
with potential as anticancer drugs tested in vitro and in vivo. The complexes have a structure …
with potential as anticancer drugs tested in vitro and in vivo. The complexes have a structure …
Synthesis, crystal structure, biological evaluation and DNA binding of three Cu (II) complexes as potential anticancer agents
K Wang, L Wang, H Li, X Yang, Z Shang, Q Han… - Journal of Molecular …, 2025 - Elsevier
In the present study, a series of copper (II) complexes containing 1, 8-naphthalimide moiety
(complexes 1–3) were synthesized and structurally characterized by Infrared spectroscopy …
(complexes 1–3) were synthesized and structurally characterized by Infrared spectroscopy …
Synthesis of benzimidazole/triphenylamine-based compounds, evaluation of their bioactivities and an in silico study with receptor tyrosine kinases
M Arulkumar, K Yang, N Wang… - New Journal of …, 2022 - pubs.rsc.org
Benzimidazole (BI)/triphenylamine (TPA)-based compounds (AL-1 to AL-7) were
synthesized and evaluated for their cytotoxic activity in different cell lines. Among them, AL-1 …
synthesized and evaluated for their cytotoxic activity in different cell lines. Among them, AL-1 …