A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

Second and third-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumour activity

GV Suárez-Moreno, D Hernández-Romero… - Coordination Chemistry …, 2022 - Elsevier
The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …

Molecular superoxide radical photogeneration in cancer cells by dipyridophenazine iridium (III) complexes

V Novohradsky, G Vigueras, J Pracharova… - Inorganic Chemistry …, 2019 - pubs.rsc.org
The phototoxicity in cancer cells of three series of octahedral Ir (III) complexes of the general
formula [Ir (C^ N) 2 (N^ N)][PF6], where the N^ N ligand is dipyrido [3, 2-a: 2′, 3′-c] …

[HTML][HTML] A 2-(benzothiazol-2-yl)-phenolato platinum (II) complex as potential photosensitizer for combating bacterial infections in lung cancer chemotherapy

E Ortega, C Pérez-Arnaiz, V Rodríguez… - European Journal of …, 2021 - Elsevier
Cancer and antibiotic resistance are two global health threats that usually hamper clinical
chemotherapeutic efficacy. Particularly for lung cancer, bacterial infections frequently arise …

Exploring the Potential of Metal‐Based Candidate Drugs as Modulators of the Cytoskeleton

Y Borutzki, L Skos, C Gerner… - …, 2023 - Wiley Online Library
During recent years, accumulating evidence suggested that metal‐based candidate drugs
are promising modulators of cytoskeletal and cytoskeleton‐associated proteins. This was …

Cyclometalated osmium compounds and beyond: Synthesis, properties, applications

R Cerón-Camacho, MA Roque-Ramires, AD Ryabov… - Molecules, 2021 - mdpi.com
The synthesis of cyclometalated osmium complexes is usually more complicated than of
other transition metals such as Ni, Pd, Pt, Rh, where cyclometalation reactions readily occur …

Fast Hydrolysis and Strongly Basic Water Adducts Lead to Potent Os (II) Half-Sandwich Anticancer Complexes

S Infante-Tadeo, V Rodríguez-Fanjul… - Inorganic …, 2022 - ACS Publications
Complexes of the formula [Os (η6-arene)(C, N-phenylpyridine) Z](where Z is chlorido or a
tethered oxygen) undergo very fast Os–Z hydrolysis (< 5 min), and the high basicity of the …

Novel organo-osmium (ii) proteosynthesis inhibitors active against human ovarian cancer cells reduce gonad tumor growth in Caenorhabditis elegans

E Ortega, FJ Ballester, A Hernández-García… - Inorganic Chemistry …, 2021 - pubs.rsc.org
This work reports the synthesis and characterization of some novel osmium (II) complexes
with potential as anticancer drugs tested in vitro and in vivo. The complexes have a structure …

Synthesis, crystal structure, biological evaluation and DNA binding of three Cu (II) complexes as potential anticancer agents

K Wang, L Wang, H Li, X Yang, Z Shang, Q Han… - Journal of Molecular …, 2025 - Elsevier
In the present study, a series of copper (II) complexes containing 1, 8-naphthalimide moiety
(complexes 1–3) were synthesized and structurally characterized by Infrared spectroscopy …

Synthesis of benzimidazole/triphenylamine-based compounds, evaluation of their bioactivities and an in silico study with receptor tyrosine kinases

M Arulkumar, K Yang, N Wang… - New Journal of …, 2022 - pubs.rsc.org
Benzimidazole (BI)/triphenylamine (TPA)-based compounds (AL-1 to AL-7) were
synthesized and evaluated for their cytotoxic activity in different cell lines. Among them, AL-1 …