Low-cost whole-genome assembly has enabled the collection of haplotype-resolved
pangenomes for numerous organisms. In turn, this technological change is encouraging the …

Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …

Recent advances in ultra-high-throughput sequencing technology and metagenomics have
led to a paradigm shift in microbial genomics from few genome comparisons to large-scale …

The pangenome provides genomic variations in the cultivated gene pool for a given species.
However, as the crop's gene pool comprises many species, especially wild relatives with …

ABSTRACT GET_HOMOLOGUES is an open-source software package that builds on
popular orthology-calling approaches making highly customizable and detailed pangenome …

Highlights•Next generation sequencing technologies have enabled large-scale genome
analyses.•Pan-genome analyses provide a framework for predicting and modeling genomic …

Horizontal transfer, gene loss, and duplication result in dynamic bacterial genomes shaped
by a complex mixture of different modes of evolution. Closely related strains can differ in the …

With the rapid development of DNA sequencing technology, increasing bacteria genome
data enable the biologists to dig the evolutionary and genetic information of prokaryotic …

The bacterial pangenome was introduced in 2005 and, in recent years, has been the subject
of many studies. Thanks to progress in next-generation sequencing methods, the …

As an increasing number of genome sequences become available for a wide range of
species, there is a growing understanding that the genome of a single individual is …