Nanoprobe-based molecular imaging for tumor stratification

X Ma, M Mao, J He, C Liang, HY **e - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Aggregation-induced emission luminogens for activity-based sensing

D Wang, BZ Tang - Accounts of Chemical Research, 2019 - ACS Publications
Conspectus Fluorescent sensing has emerged as a powerful tool for detecting various
analytes and visualizing numerous biological processes by virtue of its superb sensitivity …

Dual-locked spectroscopic probes for sensing and therapy

L Wu, J Huang, K Pu, TD James - Nature Reviews Chemistry, 2021 - nature.com
Optical imaging probes allow us to detect and uncover the physiological and pathological
functions of an analyte of interest at the molecular level in a non-invasive, longitudinal …

Fluorogenic probes for disease-relevant enzymes

J Zhang, X Chai, XP He, HJ Kim, J Yoon… - Chemical Society …, 2019 - pubs.rsc.org
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Progress and perspective of solid-state organic fluorophores for biomedical applications

K Li, TB Ren, S Huan, L Yuan… - Journal of the American …, 2021 - ACS Publications
Fluorescent organic dyes have been extensively used as raw materials for the development
of versatile imaging tools in the field of biomedicine. Particularly, the development of solid …

Harnessing endogenous stimuli for responsive materials in theranostics

AB Cook, P Decuzzi - ACS nano, 2021 - ACS Publications
Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …

Fluorescent sensors based on aggregation-induced emission: recent advances and perspectives

M Gao, BZ Tang - ACS sensors, 2017 - ACS Publications
Fluorescent sensors with advantages of excellent sensitivity, rapid response, and easy
operation are emerging as powerful tools in environmental monitoring, biological research …

Activity‐based smart AIEgens for detection, bioimaging, and therapeutics: Recent progress and outlook

H Li, H Kim, J Han, VN Nguyen, X Peng, J Yoon - Aggregate, 2021 - Wiley Online Library
Activity‐based approaches for designing AIEgens possess prominent advantages including
high selectivity, sensitivity, and signal‐to‐noise ratio, and they have received more attention …

Progress and trends in AIE-based bioprobes: a brief overview

J Mei, Y Huang, H Tian - ACS applied materials & interfaces, 2017 - ACS Publications
Luminescent bioprobes are powerful analytical means for biosensing and optical imaging.
Luminogens featured with aggregation-induced emission (AIE) attributes have emerged as …

Aggregation-induced emission: a trailblazing journey to the field of biomedicine

C Zhu, RTK Kwok, JWY Lam… - ACS Applied Bio Materials, 2018 - ACS Publications
The emergence of the aggregation-induced emission (AIE) concept significantly changes
the cognition of the scientific community toward classic photophysical phenomena. More …