Historically, the eye has been considered as an organ free of lymphatic vessels. In recent
years, however, it became evident, that lymphatic vessels or lymphatic-like vessels …

The cornea is one of the few tissues which actively maintain an avascular state, ie the
absence of blood and lymphatic vessels (corneal [lymph] angiogenic privilege). Nonetheless …

Histological studies of the lymphatic vascular system in adult mice are hampered because
bones cannot be sectioned properly. Here, we decalcified the heads of 14-day-old mice …

Simple Summary Conjunctival melanoma (CM) is a small but highly aggressive and
infiltrative periocular malignancy. Despite wide surgical excision followed by adjuvant …

Purpose.: Lymphatics subserve many important functions in the human body including
maintenance of fluid homeostasis, immune surveillance, and tumor metastasis. Our aim was …

The peripheral lymphatic system plays a crucial role in the recovery mechanisms after many
pathological changes, such as infection, trauma, vascular, or metabolic diseases. The …

The lymphatic vasculature is–amongst other tasks–essentially involved in
inflammation,(auto) immunity, graft rejection and cancer metastasis. The eye is mainly …

Aim: In this review, we outline similarities between conjunctival and skin melanoma as well
as the effectiveness of combined BRAF/MEK inhibition in melanoma, and discuss the …

Pigmented conjunctival lesions primarily include melanoma, nevus, primary acquired
melanosis (PAM), and complexion-associated melanosis. The incidence of conjunctival …

Lymphangiogenesis is a key process in cancer development and metastasis. Lymphatic
vessel endothelial hyaluronan receptor 1 (LYVE‐1) is a widely used marker for lymphatic …