CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines
involved in the development of many inflammatory diseases. It activates CXCR2 and, at high …

Chemokines play crucial roles in combating microbial infection and initiating tissue repair by
recruiting neutrophils in a timely and coordinated manner. In humans, no less than seven …

The chemokine CXCL1/MGSA plays a pivotal role in the host immune response by recruiting
and activating neutrophils for microbial killing at the tissue site. CXCL1 exists reversibly as …

The immune system is now considered a major factor in Alzheimer Disease (AD). This
review seeks to demonstrate how various aspects of the immune system, both in the brain …

Hypertension is associated with immune cells activation and their migration into the kidney,
vasculature, heart and brain. These inflammatory mechanisms are critical for blood pressure …

Chemokines play a crucial role in combating microbial infection by recruiting blood
neutrophils to infected tissue. In mice, the chemokines Cxcl1/KC and Cxcl2/MIP2 fulfill this …

Leukocyte migration into tissues depends on the activity of chemokines that form
concentration gradients to guide leukocytes to a specific site. Interaction of chemokines with …

Chemokines are a class of pro-inflammatory cytokines that can recruit and activate
chemotactic cells. C‐X‐C motif chemokine ligand 5 (CXCL5) is a member of the chemokine …

Chemokines have two types of interactions that function cooperatively to control cell
migration. Chemokine receptors on migrating cells integrate signals initiated upon …

Recruitment of immune cells from the vasculature relies on the presentation of
glycosaminoglycan-bound chemokines on the luminal side of vascular endothelial cells …