Uropathogenic Escherichia coli (UPEC)-Associated Urinary Tract Infections: The Molecular Basis for Challenges to Effective Treatment

S Whelan, B Lucey, K Finn - Microorganisms, 2023 - mdpi.com
Urinary tract infections (UTIs) are among the most common bacterial infections, especially
among women and older adults, leading to a significant global healthcare cost burden …

[PDF][PDF] Bacterial characteristics of importance for recurrent urinary tract infections caused by Escherichia coli

K Ejrnæs - Dan Med Bull, 2011 - content.ugeskriftet.dk
Urinary tract infections (UTIs) are among the most common bacterial infectious diseases
encountered in clinical practice and account for significant morbidity and high medical costs …

Virulence genes and phylogenetic groups of uropathogenic Escherichia coli isolates from patients with urinary tract infection and uninfected control subjects: a case …

SE Rezatofighi, M Mirzarazi, M Salehi - BMC Infectious Diseases, 2021 - Springer
Abstract Background Urinary Tract Infection (UTI) is one of the most common bacterial
infectious diseases which causes considerable morbidity and costly health problems …

The immune response to infection in the bladder

L Lacerda Mariano, MA Ingersoll - Nature Reviews Urology, 2020 - nature.com
The bladder is continuously protected by passive defences such as a mucus layer,
antimicrobial peptides and secretory immunoglobulins; however, these defences are …

Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections

HL Schreiber IV, MS Conover, WC Chou… - Science translational …, 2017 - science.org
Urinary tract infections (UTIs) are caused by uropathogenic Escherichia coli (UPEC) strains.
In contrast to many enteric E. coli pathogroups, no genetic signature has been identified for …

Molecular Factors and Mechanisms Driving Multidrug Resistance in Uropathogenic Escherichia coli—An Update

M Rozwadowski, D Gawel - Genes, 2022 - mdpi.com
The rapid emergence of multidrug-resistant (MDR) bacteria indisputably constitutes a major
global health problem. Pathogenic Escherichia coli are listed among the most critical group …

Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH–oligomannose-3 complex

A Wellens, C Garofalo, H Nguyen, N Van Gerven… - PLoS one, 2008 - journals.plos.org
Background Escherichia coli strains adhere to the normally sterile human uroepithelium
using type 1 pili, that are long, hairy surface organelles exposing a mannose-binding FimH …

[HTML][HTML] Multidrug-resistance and extended spectrum beta-lactamase production in uropathogenic E. coli which were isolated from hospitalized patients in Kolkata …

M Mukherjee, S BaSu, SKM MuKherjee… - Journal of clinical and …, 2013 - ncbi.nlm.nih.gov
Abstract Background and Objective: Urinary Tract Infections (UTIs) are mostly caused by
Escherichia coli. The appropriate therapy demands a current knowledge on the …

Microbial susceptibility, virulence factors, and plasmid profiles of uropathogenic Escherichia coli strains isolated from children in Jahrom, Iran

S Farshad, R Ranjbar, A Japoni, M Hosseini… - 2012 - sid.ir
Background: Urinary tract infections (UTIs), including cystitis and pyelonephritis, are the
most common infectious diseases in childhood. Escherichia coli (E. COLI) accounts for as …

Escherichia coli Bacteriocins: Antimicrobial Efficacy and Prevalence among Isolates from Patients with Bacteraemia

M Budič, M Rijavec, Ž Petkovšek, D Žgur-Bertok - PloS one, 2011 - journals.plos.org
Bacteriocins are antimicrobial peptides generally active against bacteria closely related to
the producer. Escherichia coli produces two types of bacteriocins, colicins and microcins …