[HTML][HTML] Current status of sorafenib nanoparticle delivery systems in the treatment of hepatocellular carcinoma
FH Kong, QF Ye, XY Miao, X Liu, SQ Huang, L **ong… - Theranostics, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common type of liver cancer and one of the
leading causes of cancer-related death worldwide. Advanced HCC displays strong …
leading causes of cancer-related death worldwide. Advanced HCC displays strong …
Obesity and cancer pathogenesis
NA Berger - Annals of the New York Academy of Sciences, 2014 - Wiley Online Library
Overweight and obesity have reached pandemic levels on a worldwide basis and are
associated with increased risk and worse prognosis for many but not all malignancies …
associated with increased risk and worse prognosis for many but not all malignancies …
Association of obesity with survival outcomes in patients with cancer: a systematic review and meta-analysis
Importance Obesity, defined as a body mass index (BMI) greater than 30, is associated with
a significant increase in the risk of many cancers and in overall mortality. However, various …
a significant increase in the risk of many cancers and in overall mortality. However, various …
Appropriate systemic therapy dosing for obese adult patients with cancer: ASCO guideline update
PURPOSE To provide recommendations for appropriate dosing of systemic antineoplastic
agents in obese adults with cancer. METHODS A systematic review of the literature collected …
agents in obese adults with cancer. METHODS A systematic review of the literature collected …
Sorafenib-loaded PLGA carriers for enhanced drug delivery and cellular uptake in liver cancer cells
TM Caputo, AM Cusano, S Principe… - International Journal …, 2023 - Taylor & Francis
Introduction Currently, conventional treatments of hepatocellular carcinoma (HCC) are not
selective enough for tumor tissue and lead to multidrug resistance and drug toxicity …
selective enough for tumor tissue and lead to multidrug resistance and drug toxicity …
Sex and gender differences in anticancer treatment toxicity: a call for revisiting drug dosing in oncology
The practice of oncology has dramatically changed in the last decade with the introduction of
molecular tumor profiling into routine tumor diagnostics and the extraordinary progress in …
molecular tumor profiling into routine tumor diagnostics and the extraordinary progress in …
Obesity and breast cancer: not only a risk factor of the disease
DSM Chan, T Norat - Current treatment options in oncology, 2015 - Springer
Opinion statement Obesity not only is an independent risk factor of postmenopausal breast
cancer (BC), and in particular estrogen receptor-positive/progesterone receptor-positive BC …
cancer (BC), and in particular estrogen receptor-positive/progesterone receptor-positive BC …
Messing up the cancer stem cell chemoresistance mechanisms supported by tumor microenvironment
Despite the recent advances in cancer patient management and in the development of
targeted therapies, systemic chemotherapy is currently used as a first-line treatment for …
targeted therapies, systemic chemotherapy is currently used as a first-line treatment for …
The challenges of treating patients with breast cancer and obesity
A LeVee, J Mortimer - Cancers, 2023 - mdpi.com
Simple Summary Obesity is a poor prognostic factor for patients with breast cancer, resulting
in increased risk of recurrence and death due to breast cancer. Obesity can affect both the …
in increased risk of recurrence and death due to breast cancer. Obesity can affect both the …
Evolution in medicinal chemistry of sorafenib derivatives for hepatocellular carcinoma
F Chen, Y Fang, R Zhao, J Le, B Zhang… - European Journal of …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Traditional
chemotherapy drugs are hard to reach a satisfactory therapeutic effect since advanced HCC …
chemotherapy drugs are hard to reach a satisfactory therapeutic effect since advanced HCC …