The application of nanomedicines is increasing rapidly with the promise of targeted and
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …

There is an obvious need for efficient and safe nasal absorption enhancers for the
development of therapeutically efficacious nasal products for small hydrophilic drugs …

Piperine (PIP) is a phytopharmaceutical with reported neuroprotective potential in
Alzheimer's disease (AD). Oral PIP delivery suffers from its hydrophobicity and pre-systemic …

It is well known that the central nervous system (CNS) has a limited regenerative capacity
and that many therapeutic molecules cannot cross the blood brain barrier (BBB). The use of …

The process of ionic gelation is one of the easiest ways to develop chitosan nanoparticles
reported so far in the literature. Its success is mainly due to its one-shot synthesis, and to the …

The discovery of effective drugs for the treatment of neurodegenerative disorders (NDs) is a
deadlock. Due to their complex etiology and high heterogeneity, progresses in the …

Alzheimer's disease (AD), the most common form of dementia, has increasing incidence,
increasing mortality rates, and poses a huge burden on healthcare. None of the currently …

Rivastigmine is a drug commonly used in the management of Alzheimer's disease that
shows bioavailability problems. To overcome this, the use of nanosystems, such as …

Aims Among polyphenolic phytoconstituents with anticancer properties, Ellagic acid (EA) is
widely reported for its translational potential in vitro but efficient in vivo delivery of EA has …

The major impediment to the delivery of therapeutics to the brain is the presence of the
blood-brain barrier (BBB). The BBB allows for the entrance of essential nutrients while …