Mast cells in the autonomic nervous system and potential role in disorders with dysautonomia and neuroinflammation

TC Theoharides, A Twahir, D Kempuraj - Annals of Allergy, Asthma & …, 2024 - Elsevier
Mast cells (MC) are ubiquitous in the body, and they are critical for not only in allergic
diseases but also in immunity and inflammation, including having potential involvement in …

Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis

S Antoun, P Ellul, H Peyre, M Rosenzwajg, P Gressens… - Molecular autism, 2021 - Springer
Background Fever during pregnancy is a relatively common and most often trivial event.
However, under specific conditions, it could affect significantly fetal brain development. Few …

Exposure to prenatal infection and the development of internalizing and externalizing problems in children: a longitudinal population‐based study

A Suleri, AS Rommel, A Neumann… - Journal of Child …, 2024 - Wiley Online Library
Background A large body of work has reported a link between prenatal exposure to infection
and increased psychiatric risk in offspring. However, studies to date have focused primarily …

Sex-specific pathways from prenatal maternal inflammation to adolescent depressive symptoms

E Lipner, N Mac Giollabhui, EC Breen, BA Cohn… - JAMA …, 2024 - jamanetwork.com
Importance Prenatal maternal inflammation has been associated with major depressive
disorder in offspring in adulthood as well as with internalizing and externalizing symptoms in …

Associations between prenatal maternal stress, maternal inflammation during pregnancy, and children's internalizing and externalizing symptoms throughout …

ZM Clayborne, R Zou, SE Gilman… - Brain, behavior, and …, 2023 - Elsevier
Background Maternal immune activation is a potential mechanism underlying associations
between maternal stress during pregnancy and offspring mental health problems. This study …

Mast Cells in Autism Spectrum Disorder—The Enigma to Be Solved?

E Kovacheva, M Gevezova, M Maes… - International Journal of …, 2024 - mdpi.com
Autism Spectrum Disorder (ASD) is a disturbance of neurodevelopment with a complicated
pathogenesis and unidentified etiology. Many children with ASD have a history of “allergic …

The association between prenatal infection and adolescent behavior: Investigating multiple prenatal, perinatal, and childhood second hits

A Suleri, T White, E Blok, CAM Cecil, I Reiss… - Journal of the American …, 2023 - Elsevier
Objective Exposure to infections during pregnancy may be a potential risk factor for later
psychopathology, but large-scale epidemiological studies investigating associations …

Association between cumulative maternal exposures related to inflammation and child attention‐deficit/hyperactivity disorder: a cohort study

TC Nielsen, N Nassar, AW Shand… - Paediatric and …, 2024 - Wiley Online Library
Background Preclinical studies suggest synergistic effects of maternal inflammatory
exposures on offspring neurodevelopment, but human studies have been limited. Objectives …

[HTML][HTML] Ways to address perinatal mast cell activation and focal brain inflammation, including response to SARS-CoV-2, in autism spectrum disorder

TC Theoharides - Journal of Personalized Medicine, 2021 - mdpi.com
The prevalence of autism spectrum disorder (ASD) continues to increase, but no distinct
pathogenesis or effective treatment are known yet. The presence of many comorbidities …

Types of diabetes during pregnancy and risk of depression and anxiety in offspring from childhood to young adulthood

AH **ang, JC Lin, T Chow, MP Martinez… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aims To assess maternal pre‐existing type 1 diabetes (T1D), type 2 diabetes (T2D),
gestational diabetes mellitus (GDM) during pregnancy and risk of depression and anxiety …