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Factors that influence the immune response to vaccination
There is substantial variation between individuals in the immune response to vaccination. In
this review, we provide an overview of the plethora of studies that have investigated factors …
this review, we provide an overview of the plethora of studies that have investigated factors …
Host factors impact vaccine efficacy: implications for seasonal and universal influenza vaccine programs
Influenza is a global public health problem. Current seasonal influenza vaccines have highly
variable efficacy, and thus attempts to develop broadly protective universal influenza …
variable efficacy, and thus attempts to develop broadly protective universal influenza …
HLA-DRB1 the notorious gene in the mosaic of autoimmunity
The major histocompatibility complex system is the most polymorphic gene cluster of the
mammal genome. In humans, this is a genomic locus known as the human leukocyte …
mammal genome. In humans, this is a genomic locus known as the human leukocyte …
HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy
Type 1 narcolepsy, a disorder caused by a lack of hypocretin (orexin), is so strongly
associated with human leukocyte antigen (HLA) class II HLA-DQA1∗ 01: 02-DQB1∗ 06: 02 …
associated with human leukocyte antigen (HLA) class II HLA-DQA1∗ 01: 02-DQB1∗ 06: 02 …
Factors affecting immune responses to the influenza vaccine
MR Castrucci - Human vaccines & immunotherapeutics, 2018 - Taylor & Francis
Annual administration of the seasonal influenza vaccine is strongly recommended to reduce
the burden of disease, particularly for persons at the highest risk for the viral infection. Even …
the burden of disease, particularly for persons at the highest risk for the viral infection. Even …
Systems vaccinology: enabling rational vaccine design with systems biological approaches
Vaccines have drastically reduced the mortality and morbidity of many diseases. However,
vaccines have historically been developed empirically, and recent development of vaccines …
vaccines have historically been developed empirically, and recent development of vaccines …
[HTML][HTML] RTS, S malaria vaccine efficacy and immunogenicity during Plasmodium falciparum challenge is associated with HLA genotype
Although RTS, S remains the most advanced malaria vaccine, the factors influencing
differences in vaccine immunogenicity or efficacy between individuals or populations are still …
differences in vaccine immunogenicity or efficacy between individuals or populations are still …
Factors influencing the immunogenicity of influenza vaccines
S Wen, Z Wu, S Zhong, M Li, Y Shu - Human vaccines & …, 2021 - Taylor & Francis
Annual vaccination is the best prevention of influenza. However, the immunogenicity of
influenza vaccines varies among different populations. It is important to fully identify the …
influenza vaccines varies among different populations. It is important to fully identify the …
HLA alleles measured from COVID-19 patient transcriptomes reveal associations with disease prognosis in a New York cohort
Background The Human Leukocyte Antigen (HLA) gene locus plays a fundamental role in
human immunity, and it is established that certain HLA alleles are disease determinants …
human immunity, and it is established that certain HLA alleles are disease determinants …
Retrospective in silico HLA predictions from COVID-19 patients reveal alleles associated with disease prognosis
Background: The Human Leukocyte Antigen (HLA) gene locus plays a fundamental role in
human immunity, and it is established that certain HLA alleles are disease determinants …
human immunity, and it is established that certain HLA alleles are disease determinants …