Nanoemulgel: a novel nano carrier as a tool for topical drug delivery

MR Donthi, SR Munnangi, KV Krishna, RN Saha… - Pharmaceutics, 2023 - mdpi.com
Nano-emulgel is an emerging drug delivery system intended to enhance the therapeutic
profile of lipophilic drugs. Lipophilic formulations have a variety of limitations, which includes …

Cellulose derivatives and natural gums as gelling agents for preparation of emulgel-based dosage forms: A brief review

MAR Estabragh, MS Bami, G Dehghannoudeh… - International Journal of …, 2023 - Elsevier
Incorporation of an emulsion onto a gel base develops a drug delivery system with improved
characteristics, known as emulgel, that can envelop both hydrophilic and lipophilic …

Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

M Yu, W Liu, J Li, J Lu, H Lu, W Jia, F Liu - Stem cell research & therapy, 2020 - Springer
Background Mesenchymal stem cell (MSC)-derived exosomes emerge as promising
candidates for treating delayed wound healing in diabetes due to the promotion of …

[HTML][HTML] Intranasal delivery of Clozapine using nanoemulsion-based in-situ gels: An approach for bioavailability enhancement

NA Abdulla, GF Balata, HA El-Ghamry… - Saudi Pharmaceutical …, 2021 - Elsevier
Limited solubility and hepatic first-pass metabolism are the main causes of low
bioavailability of anti-schizophrenic drug, Clozapine (CZP). The objective of the study was to …

Preparation, characterization and evaluation of anti-inflammatory and anti-nociceptive effects of brucine-loaded nanoemulgel

MH Abdallah, ASA Lila, R Unissa, HS Elsewedy… - Colloids and Surfaces B …, 2021 - Elsevier
Brucine (BRU) is a natural product derived from nux-vomica seeds. It is commonly used as
an anti-inflammatory and anti-nociceptive drug to relieve arthritis and traumatic pain …

[HTML][HTML] Development and optimization of naringenin-loaded chitosan-coated nanoemulsion for topical therapy in wound healing

SH Akrawi, B Gorain, AB Nair, H Choudhury, M Pandey… - Pharmaceutics, 2020 - mdpi.com
The potential role of naringenin (NAR), a natural flavonoid, in the treatment of chronic wound
has prompted the present research to deliver the drug in nanoemulsion (NE) form, where …

Nanoemulgel: A promising novel formulation for treatment of skin ailments

B Ojha, VK Jain, S Gupta, S Talegaonkar, K Jain - Polymer Bulletin, 2022 - Springer
Nanoemulgel is an emanating drug delivery system particularly being explored in research
and development of various topical formulations for both pharmaceutical and cosmeceutical …

Intranasal delivery of darunavir-loaded mucoadhesive in situ gel: Experimental design, in vitro evaluation, and pharmacokinetic studies

AB Nair, S Chaudhary, H Shah, S Jacob, V Mewada… - Gels, 2022 - mdpi.com
The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low
perfusion of the drug to the brain. The objective of the current investigation was to design …

Natural oils enhance the topical delivery of ketoconazole by nanoemulgel for fungal infections

I Ahmad, M Farheen, A Kukreti, O Afzal, MH Akhter… - ACS …, 2023 - ACS Publications
Nanoemulgel (NEG) pharmaceutical formulations are gaining popularity because of their
ability to serve both as a nanoemulsion and as a gel. These products are well-known for …

Wound healing potential of insulin-loaded nanoemulsion with Aloe vera gel in diabetic rats

T Chakraborty, S Gupta, A Nair, S Chauhan… - Journal of Drug Delivery …, 2021 - Elsevier
Diabetes skin infection is a very common disorder in hyperglycemic patients. This study
evaluated the prospective of develo** a topical gel formulation of Aloe vera with insulin …