The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

Transition metal-catalysed carbene-and nitrene transfer to the C1-building blocks carbon
monoxide and isocyanides provides heteroallenes (ie ketenes, isocyanates, ketenimines …

Polyheterocycles are one of the most desired synthetic targets due to their numerous and
valuable applications in various fields. Multicomponent reactions (MCRs) are highly …

More than 60 years have passed since I. Ugi synthesized the first α-amidoamides in one
experimental step involving a combination of aldehydes, amines, carboxylic acids and …

The advent of cycloaddition reactions in the synthesis of heterocycles and their ever
burgeoning applications in the fields of material chemistry, catalysis and drugs have been a …

A novel iodine-catalyzed functionalization of a variety of olefins and alkynes and direct
decarboxylative functionalization of cinnamic and propiolic acids with TosMIC to provide …

Pyrroles are among the most privileged and influential small N-heterocycles at the core of
many commercial drugs, biological composition, natural compounds, agrochemicals, and …

Abstract p‐tosylmethyl isocyanide (TosMIC) which is also known as van Leusen's reagent
hold the three functionalized groups including the isocyanide and sulfonyl group and an …

A planning strategy for diversity‐oriented catalyst-free synthesis of pseudopeptides
containing rhodanine scaffolds has been developed via a novel one-pot sequential six …

We report an I2/FeCl3-co-promoted formal [2+ 2+ 1] annulation of aryl methyl ketones, 2-
aminobenzyl alcohols, and p-toluenesulfonylmethyl isocyanide (TosMIC) by neighboring …